Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 14/20 | 0.38 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.37 |
| ▸ | ULK1 | O75385 | 1/20 | 0.35 |
| ▸ | ULK2 | Q8IYT8 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26105753 | 0.81 | TRPV1 (0.44) | TRPV1MAPT | |
| SCHEMBL30591713 | 0.78 | TEAD1 (0.55) | EGFR | |
| SCHEMBL26108164 | 0.78 | FAAH (0.42) | TRPV1 | |
| SCHEMBL26111646 | 0.77 | TRPV1 (0.40) | TRPV1 | |
| SCHEMBL26107483 | 0.76 | TRPV1 (0.46) | TRPV1 | |
| SCHEMBL21856357 | 0.75 | RHOC (0.40) | PAK1 | |
| SCHEMBL21856323 | 0.73 | IDH2 (0.45) | — | |
| SCHEMBL21856343 | 0.73 | TAS2R14 (0.37) | — | |
| SCHEMBL21856319 | 0.73 | ALDH1A1 (0.42) | TRPV1MAPTPOLB | |
| SCHEMBL21856354 | 0.73 | EGFR (0.39) | EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023183768-A2 | SMALL MOLECULE INHIBITORS OF TEA DOMAIN FAMILY MEMBERS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2023-09-28 | — | — | WO | disclosed |