Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHUK | O15111 | 6/20 | 0.49 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.43 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.43 |
| ▸ | CDC42BPA | Q5VT25 | 2/20 | 0.43 |
| ▸ | CDC42BPB | Q9Y5S2 | 2/20 | 0.43 |
| ▸ | DPYD | Q12882 | 1/20 | 0.43 |
| ▸ | HSP90AB1 | P08238 | 5/20 | 0.42 |
| ▸ | LRRK2 | Q5S007 | 5/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | IKBKB | O14920 | 3/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL94358 | 0.81 | CHUK (0.56) | CHUKDPYDLRRK2IKBKB | |
| SCHEMBL7842455 | 0.80 | PARP1 (0.36) | CHUK | |
| SCHEMBL7851196 | 0.75 | TYMS (0.48) | DPYD | |
| SCHEMBL20012256 | 0.74 | ALDH1A1 (0.47) | CHUKROCK2ROCK1CDC42BPACDC42BPB | |
| SCHEMBL26232177 | 0.73 | TYMS (0.41) | — | |
| SCHEMBL7854494 | 0.72 | TYMS (0.43) | GAAHSP90AA1 | |
| SCHEMBL17652022 | 0.70 | CHUK (0.43) | CHUKROCK2ROCK1CDC42BPACDC42BPB | |
| SCHEMBL19992162 | 0.70 | PARP1 (0.64) | GAA | |
| SCHEMBL7851328 | 0.70 | DAO (0.33) | GAA | |
| SCHEMBL29559852 | 0.69 | MAPK1 (0.39) | GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230295165-A1 | COMPOUNDS | THE PROVOST, FELLOWS, FOUNDATION SCHOLARS, AND THE OTHER MEMBERS OF BOARD, OF THE COLLEGE OF THE HOLY AND UNDIVIDED TRINITY OF QUEEN ELIZABETH, NEAR DUBLIN (IE) | 2023-09-21 | — | — | US | disclosed |
| US-20230286987-A1 | COMPOUNDS | THE PROVOST, FELLOWS, FOUNDATION SCHOLARS, AND THE OTHER MEMBERS OF BOARD, OF THE COLLEGE OF THE HOLY AND UNDIVIDED TRINITY OF QUEEN ELIZABETH, NEAR DUBLIN (IE) | 2023-09-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230295165-A1 | COMPOUNDS | NR3C1, NR3C2, CBR3 | CHUK 1812/4885ROCK2 2054/4885ROCK1 926/4885 |
| US-20230286987-A1 | COMPOUNDS | HAX1, NHERF1, CXCR1 | CHUK 1560/4885ROCK2 1911/4885ROCK1 527/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.