Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 2/20 | 0.38 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.36 |
| ▸ | RAD52 | P43351 | 1/20 | 0.36 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | KCNN4 | O15554 | 2/20 | 0.32 |
| ▸ | KCNA3 | P22001 | 2/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | BRD2 | P25440 | 1/20 | 0.32 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL919720 | 0.90 | MEN1 (0.38) | HTR7KMT2AMEN1CYP1A2CYP2A6 | |
| SCHEMBL19259323 | 0.80 | ALDH1A1 (0.36) | HTR7KMT2AMEN1CYP1A2CYP2A6 | |
| SCHEMBL23894717 | 0.74 | L3MBTL1 (0.37) | KMT2AMEN1CYP1A2CYP2A6L3MBTL1 | |
| SCHEMBL23186684 | 0.74 | MGLL (0.40) | HTR7KMT2AMEN1L3MBTL1ALDH1A1 | |
| SCHEMBL23186696 | 0.74 | HTR7 (0.38) | HTR7KMT2AMEN1L3MBTL1ALDH1A1 | |
| SCHEMBL820145 | 0.73 | ALDH1A1 (0.35) | NPSR1ALDH1A1SMN1; SMN2 | |
| SCHEMBL17929854 | 0.72 | KMT2A (0.36) | HTR7KMT2AMEN1CYP1A2CYP2A6 | |
| Hydrochloric Acid SCHEMBL819271 | 0.71 | ALDH1A1 (0.34) | NPSR1ALDH1A1SMN1; SMN2 | |
| SCHEMBL760838 | 0.70 | ALDH1A1 (0.33) | NPSR1ALDH1A1SMN1; SMN2 | |
| SCHEMBL2126293 | 0.70 | ALDH1A1 (0.33) | NPSR1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8163900-B2 | Seven-membered heterocyclic carbenes and their metal complexes | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2012-04-24 | — | — | US | disclosed |
| US-20100228024-A1 | SEVEN-MEMBERED HETEROCYCLIC CARBENES AND THEIR METAL COMPLEXES | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2010-09-09 | — | — | US | disclosed |
| US-7750149-B2 | Seven-membered heterocyclic carbenes and their metal complexes | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2010-07-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100228024-A1 | SEVEN-MEMBERED HETEROCYCLIC CARBENES AND THEIR METAL COMPLEXES | CYCS, COG7, SOD1 | HTR7 635/4885DNMT1 978/4885RAD52 955/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.