SCHEMBL2628342

SCHEMBL2628342

Cn1c2cccnc2c2ncccc21

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADORA3 P0DMS8 2/20 0.54
ADORA2A P29274 2/20 0.54
MAPK14 Q16539 1/20 0.46
HSP90AA1 P07900 2/20 0.44
NPC1 O15118 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
HTT P42858 2/20 0.44
LMNA P02545 2/20 0.44
MMP2 P08253 2/20 0.44
TSHR P16473 2/20 0.44
KDM4E B2RXH2 1/20 0.44
GMNN O75496 1/20 0.44
TP53 P04637 1/20 0.44
CYP3A4 P08684 1/20 0.44
CYP2D6 P10635 1/20 0.44
MAPT P10636 1/20 0.44
MMP9 P14780 1/20 0.44
ALOX15 P16050 1/20 0.44
NFKB1 P19838 1/20 0.44
MMP8 P22894 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13183589 0.87 ADORA3 (0.61) ADORA3ADORA2AMAPK14HSP90AA1NPC1
SCHEMBL31232963 0.85 GPR3 (0.58) ADORA3ADORA2AMAPK14HSP90AA1NPC1
SCHEMBL2628393 0.85 ADORA3 (0.44) ADORA3ADORA2AMAPK14HSP90AA1NPC1
SCHEMBL1609786 0.85 GPR3 (0.58) ADORA3ADORA2AMAPK14HSP90AA1NPC1
SCHEMBL18381851 0.84 GPR3 (0.57) ADORA3ADORA2AHSP90AA1NPC1L3MBTL1
SCHEMBL2628391 0.84 MAPK14 (0.44) ADORA3ADORA2AMAPK14HSP90AA1NPC1
SCHEMBL13183748 0.83 ADORA3 (0.50) ADORA3ADORA2AMAPK14HSP90AA1NPC1
SCHEMBL18381781 0.82 GPR3 (0.59) ADORA3ADORA2AMAPK14HSP90AA1NPC1
SCHEMBL9968114 0.82 ADORA3 (0.42) ADORA3ADORA2AMAPK14HSP90AA1NPC1
SCHEMBL14191775 0.81 ADORA3 (0.51) ADORA3ADORA2AMAPK14HSP90AA1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 119 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230389421-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-11-30 US disclosed
US-20230389421-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-11-30 US disclosed
US-20230329086-A1 ORGANOMETALLIC COMPOUND AND LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2023-10-12 US disclosed
US-20230301170-A1 ORGANOMETALLIC COMPOUND, LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND ELECTRONIC APPARATUS INCLUDING THE LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2023-09-21 US disclosed
US-20230286989-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-09-14 US disclosed
US-20230225147-A1 ORGANIC LIGHT-EMITTING ELEMENT KYULUX, INC. (JP) 2023-07-13 US disclosed
US-20230225147-A1 ORGANIC LIGHT-EMITTING ELEMENT KYULUX, INC. (JP) 2023-07-13 US disclosed
US-20230217806-A1 LIGHT-EMITTING DEVICE, ELECTRONIC APPARATUS INCLUDING THE SAME, AND ORGANOMETALLIC COMPOUND SAMSUNG DISPLAY CO., LTD. (KR) 2023-07-06 US disclosed
US-11637244-B2 Light-emitting material, compound, and organic light-emitting element KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2023-04-25 US disclosed
US-11335872-B2 Organic light-emitting device KYULUX, INC. (JP) 2022-05-17 US disclosed
US-20080088230-A1 Organic electroluminescent element and display KONICA MINOLTA HOLDINGS, INC. (JP) 2008-04-17 US disclosed
US-20080088230-A1 Organic electroluminescent element and display KONICA MINOLTA HOLDINGS, INC. (JP) 2008-04-17 US disclosed
US-20080067925-A1 organic EL element showing high light emission efficiency and high color purity of the emission light, an organic EL element, a lighting device and a displaying device each using the metal complex is represented by the Formula 1 or isomer KONICA MINOLTA HOLDINGS, INC. (JP) 2008-03-20 US disclosed
US-20080067925-A1 organic EL element showing high light emission efficiency and high color purity of the emission light, an organic EL element, a lighting device and a displaying device each using the metal complex is represented by the Formula 1 or isomer KONICA MINOLTA HOLDINGS, INC. (JP) 2008-03-20 US disclosed
US-20080038586-A1 White Light Emitting Organic Electroluminescence Element, Display and Illuminator KONICA MINOLTA HOLDINGS, INC. (JP) 2008-02-14 US disclosed
US-20080038586-A1 White Light Emitting Organic Electroluminescence Element, Display and Illuminator KONICA MINOLTA HOLDINGS, INC. (JP) 2008-02-14 US disclosed
US-7326475-B2 Material for organic electroluminescent device, organic electroluminescent device, illuminating device and display KONICA MINOLTA HOLDINGS, INC. (JP) 2008-02-05 US disclosed
US-7326475-B2 Material for organic electroluminescent device, organic electroluminescent device, illuminating device and display KONICA MINOLTA HOLDINGS, INC. (JP) 2008-02-05 US disclosed
US-20070132372-A1 AMINE BASED COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2007-06-14 US disclosed
US-20070132372-A1 AMINE BASED COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2007-06-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070132372-A1 AMINE BASED COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME KCNH2, SLC7A5, KCNH3 ADORA3 1303/4885ADORA2A 761/4885MAPK14 1508/4885
US-20230301170-A1 ORGANOMETALLIC COMPOUND, LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND ELECTRONIC APPARATUS INCLUDING THE LIGHT-EMITTING DEVICE LAGE3, GPX1, LEF1 ADORA3 4655/4885ADORA2A 4512/4885MAPK14 4027/4885
US-11637244-B2 Light-emitting material, compound, and organic light-emitting element RPLP2, OPRD1, POLL ADORA3 2711/4885ADORA2A 3285/4885MAPK14 4361/4885
US-20230286989-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, ODC1 ADORA3 3512/4885ADORA2A 3169/4885MAPK14 4155/4885
US-20230329086-A1 ORGANOMETALLIC COMPOUND AND LIGHT-EMITTING DEVICE INCLUDING THE SAME LAGE3, LEF1, EML4 ADORA3 4476/4885ADORA2A 4527/4885MAPK14 3399/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.