SCHEMBL26298608

SCHEMBL26298608

Cc1[nH]c2c3ccccc3n(C)c2c1C(C)C

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALKBH5 Q6P6C2 1/20 0.45
▸ FTO Q9C0B1 1/20 0.45
▸ KDM4E B2RXH2 4/20 0.44
▸ MAPT P10636 1/20 0.44
▸ GPR3 P46089 1/20 0.42
▸ GABRP O00591 2/20 0.40
▸ GABRD O14764 2/20 0.40
▸ GABRA1 P14867 2/20 0.40
▸ GABRB1 P18505 2/20 0.40
▸ GABRG2 P18507 2/20 0.40
▸ GABRB3 P28472 2/20 0.40
▸ GABRA5 P31644 2/20 0.40
▸ GABRA3 P34903 2/20 0.40
▸ GABRA2 P47869 2/20 0.40
▸ GABRB2 P47870 2/20 0.40
▸ GABRA4 P48169 2/20 0.40
▸ GABRE P78334 2/20 0.40
▸ GABRA6 Q16445 2/20 0.40
▸ GABRG1 Q8N1C3 2/20 0.40
▸ GABRG3 Q99928 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26168264 0.81 KDM4E (0.39) KDM4EMAPTALDH1A1GAAMEN1
SCHEMBL26298560 0.76 LMNA (0.44) ALKBH5FTOKDM4EMAPTGPR3
SCHEMBL26168256 0.76 KDM4E (0.42) ALKBH5FTOKDM4EMAPTGPR3
SCHEMBL26297267 0.73 ALKBH5 (0.47) ALKBH5FTOKDM4EMAPTGPR3
SCHEMBL17029497 0.73 CDK4 (0.55) ALKBH5FTOKDM4EMAPTGPR3
SCHEMBL20153649 0.72 ALKBH5 (0.59) ALKBH5FTOKDM4EMAPTGPR3
SCHEMBL17616023 0.72 GPR3 (0.52) ALKBH5FTOKDM4EMAPTGPR3
SCHEMBL8704226 0.70 ALDH1A1 (0.46) KDM4EMAPTALDH1A1GAAMEN1
SCHEMBL26168266 0.70 ALKBH5 (0.44) ALKBH5FTOKDM4EMAPTGPR3
SCHEMBL25786912 0.68 GPR3 (0.47) ALKBH5FTOKDM4EMAPTGPR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230276696-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORP (US) 2023-08-31 — — US disclosed
US-11678565-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-06-13 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11678565-B2 Organic electroluminescent materials and devices OCIAD1, OCIAD2, OPRD1 ALKBH5 1213/4885FTO 601/4885KDM4E 3475/4885
US-20230276696-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, PORCN ALKBH5 666/4885FTO 480/4885KDM4E 3190/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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