Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.46 |
| ▸ | HPGD | P15428 | 7/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | KLK7 | P49862 | 1/20 | 0.42 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26298560 | 0.86 | LMNA (0.44) | ALDH1A1HPGDKDM4EKMT2AHSD17B10 | |
| SCHEMBL8696580 | 0.78 | ALDH1A1 (0.46) | ALDH1A1HPGDKDM4EKMT2AHSD17B10 | |
| SCHEMBL27566954 | 0.71 | PTGS2 (0.62) | ALDH1A1HPGDKDM4EKMT2AHSD17B10 | |
| SCHEMBL7035424 | 0.71 | L3MBTL1 (0.68) | ALDH1A1HPGDKDM4EKMT2AHSD17B10 | |
| SCHEMBL26298608 | 0.70 | ALKBH5 (0.45) | ALDH1A1HPGDKDM4EKMT2AHSD17B10 | |
| SCHEMBL28593695 | 0.70 | GRIK2 (0.67) | ALDH1A1HPGDKDM4EKMT2AHSD17B10 | |
| SCHEMBL13563978 | 0.68 | MAPT (0.57) | ALDH1A1HPGDKDM4EKMT2AHSD17B10 | |
| SCHEMBL1470672 | 0.67 | ACHE (0.61) | ALDH1A1HPGDKDM4EHTTMAPT | |
| SCHEMBL29458789 | 0.67 | ACHE (0.61) | ALDH1A1HPGDKDM4EHTTMAPT | |
| SCHEMBL11266587 | 0.67 | LMNA (0.50) | ALDH1A1HPGDKDM4EKMT2AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998042709-A1 | ENDOTHELIN-RECEPTOR ANTAGONISTS | MERCK PATENT GMBH (DE) | 1998-10-01 | — | — | WO | disclosed |