Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.36 |
| ▸ | NQO1 | P15559 | 3/20 | 0.35 |
| ▸ | POR | P16435 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25401356 | 0.80 | CRHR1 (0.40) | L3MBTL1CRHR1 | |
| SCHEMBL23567062 | 0.79 | ADRA1D (0.50) | ALDH1A1CYP3A4SMN1; SMN2TSHRHSD17B10 | |
| SCHEMBL26316367 | 0.77 | PTGS2 (0.34) | POLBSMN1; SMN2ADRA1DADRA1AADRA1B | |
| SCHEMBL9938324 | 0.77 | ACHE (0.68) | ACHEALDH1A1CYP3A4POLBSMN1; SMN2 | |
| SCHEMBL13393531 | 0.75 | NQO1 (0.37) | ALDH1A1NQO1PORMEN1HPGD | |
| SCHEMBL16542335 | 0.74 | ACHE (0.58) | ACHEALDH1A1CYP3A4POLBSMN1; SMN2 | |
| SCHEMBL26273690 | 0.71 | HTR2A (0.35) | ALDH1A1HSD17B10HPGD | |
| SCHEMBL13481179 | 0.70 | IMPDH2 (0.49) | ACHEALDH1A1CYP3A4POLBSMN1; SMN2 | |
| SCHEMBL10137021 | 0.70 | ACHE (0.58) | ACHEALDH1A1CYP3A4SMN1; SMN2MAPT | |
| SCHEMBL13069497 | 0.69 | ACHE (0.52) | ACHEALDH1A1CYP3A4SMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230295113-A1 | NLRP3 MODULATORS | ZOMAGEN BIOSCIENCES LTD | 2023-09-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230295113-A1 | NLRP3 MODULATORS | NLRP3, NLRP1, NOD1 | ACHE 4865/4885ALDH1A1 2633/4885CYP3A4 1539/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.