Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 4/20 | 1.00 |
| ▸ | ROCK1 | Q13464 | 4/20 | 1.00 |
| ▸ | PKN2 | Q16513 | 3/20 | 0.79 |
| ▸ | RPS6KA5 | O75582 | 2/20 | 0.79 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.79 |
| ▸ | TP53 | P04637 | 2/20 | 0.79 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.79 |
| ▸ | TSHR | P16473 | 2/20 | 0.79 |
| ▸ | CHUK | O15111 | 1/20 | 0.79 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.79 |
| ▸ | CDK1 | P06493 | 1/20 | 0.79 |
| ▸ | CDK2 | P24941 | 1/20 | 0.79 |
| ▸ | LTK | P29376 | 1/20 | 0.79 |
| ▸ | CDK8 | P49336 | 1/20 | 0.79 |
| ▸ | PRKX | P51817 | 1/20 | 0.79 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.79 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.79 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.79 |
| ▸ | STK3 | Q13188 | 1/20 | 0.79 |
| ▸ | PRKG2 | Q13237 | 1/20 | 0.79 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14492963 | 1.00 | ROCK2 (1.00) | ROCK2ROCK1PKN2RPS6KA5LRRK2 | |
| SCHEMBL26318572 | 0.90 | ROCK2 (0.81) | ROCK2ROCK1PKN2RPS6KA5LRRK2 | |
| Y-27632 SCHEMBL1980406 | 0.88 | ROCK2 (1.00) | ROCK2ROCK1PKN2RPS6KA5LRRK2 | |
| Y-27632 SCHEMBL18935698 | 0.88 | ROCK2 (1.00) | ROCK2ROCK1PKN2RPS6KA5LRRK2 | |
| Y-27632 SCHEMBL20333114 | 0.88 | ROCK2 (1.00) | ROCK2ROCK1PKN2RPS6KA5LRRK2 | |
| Y-27632 SCHEMBL190356 | 0.88 | ROCK2 (1.00) | ROCK2ROCK1PKN2RPS6KA5LRRK2 | |
| Y-27632 SCHEMBL598993 | 0.88 | ROCK2 (1.00) | ROCK2ROCK1PKN2RPS6KA5LRRK2 | |
| Y-27632 SCHEMBL342816 | 0.88 | ROCK2 (1.00) | ROCK2ROCK1PKN2RPS6KA5LRRK2 | |
| Y-27632 SCHEMBL30286315 | 0.88 | ROCK2 (1.00) | ROCK2ROCK1PKN2RPS6KA5LRRK2 | |
| Y-27632 SCHEMBL28416532 | 0.88 | ROCK2 (1.00) | ROCK2ROCK1PKN2RPS6KA5LRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230255980-A1 | TASTE-MASKING ORAL FORMULATIONS OF FASUDIL | WOOLSEY PHARMACEUTICALS, INC. | 2023-08-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230255980-A1 | TASTE-MASKING ORAL FORMULATIONS OF FASUDIL | ROCK1, TAS2R42, MOK | ROCK2 4/4885ROCK1 1/4885PKN2 754/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.