SCHEMBL26375409

SCHEMBL26375409

Cc1ccc(C(F)(F)F)c(-c2ccccc2C(F)(F)F)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 9/20 0.50
TRPA1 O75762 2/20 0.46
TRPM8 Q7Z2W7 1/20 0.46
TRPV1 Q8NER1 1/20 0.46
PDK2 Q15119 2/20 0.46
ELANE P08246 1/20 0.44
CYP3A4 P08684 4/20 0.43
CYP1A2 P05177 3/20 0.43
ALOX15 P16050 3/20 0.43
HSD17B10 Q99714 3/20 0.43
ALDH1A1 P00352 3/20 0.43
CYP2D6 P10635 2/20 0.43
TSHR P16473 2/20 0.43
CYP2C19 P33261 2/20 0.43
TDP1 Q9NUW8 2/20 0.43
LMNA P02545 1/20 0.43
MAPK1 P28482 2/20 0.41
HIF1A Q16665 1/20 0.41
HPGD P15428 1/20 0.41
AR P10275 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10343225 0.89 TRPA1 (0.51) HSD11B1TRPA1TRPM8TRPV1PDK2
SCHEMBL22171634 0.88 HSD11B1 (0.50) HSD11B1TRPA1TRPM8TRPV1PDK2
SCHEMBL26375371 0.87 HSD11B1 (0.44) HSD11B1TRPA1PDK2ELANEHPGD
SCHEMBL13147201 0.85 TRPA1 (0.51) HSD11B1TRPA1TRPM8TRPV1PDK2
SCHEMBL23149011 0.82 HSD11B1 (0.46) HSD11B1TRPA1PDK2ELANECYP3A4
SCHEMBL29616670 0.82 HSD11B1 (0.46) HSD11B1TRPA1PDK2ELANECYP3A4
SCHEMBL15931132 0.82 ACHE (0.44) HSD11B1TRPA1TRPM8TRPV1PDK2
SCHEMBL26375448 0.80 KIF11 (0.49) HSD11B1PDK2CYP3A4CYP2D6MAPK1
SCHEMBL197671 0.80 HSD11B1 (0.56) HSD11B1TRPA1TRPM8TRPV1CYP3A4
SCHEMBL18240867 0.79 ELANE (0.41) HSD11B1TRPA1TRPM8TRPV1PDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230309388-A1 ORGANIC ELECTROLUMINESCENT MATERIAL AND DEVICE Beijing Summer Sprout Technology Co., Ltd. (CN) 2023-09-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230309388-A1 ORGANIC ELECTROLUMINESCENT MATERIAL AND DEVICE OCIAD1, OCIAD2, SLCO4C1 HSD11B1 608/4885TRPA1 280/4885TRPM8 652/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.