Sugi Predict

Sugi Predict / Compounds / SCHEMBL264135

SCHEMBL264135

SCHEMBL264135

CC1(C)OB(c2cc(O)ccc2Cl)OC1(C)C

nearest known ligand 0.42

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ HSD17B10 Q99714 1/20 0.42
▸ CA1 P00915 3/20 0.38
▸ CA2 P00918 3/20 0.38
▸ CA9 Q16790 3/20 0.38
▸ CA12 O43570 2/20 0.38
▸ CA7 P43166 2/20 0.38
▸ CA14 Q9ULX7 2/20 0.38
▸ ESR1 P03372 6/20 0.36
▸ ESR2 Q92731 3/20 0.36
▸ LPL P06858 4/20 0.33
▸ LIPG Q9Y5X9 4/20 0.33
▸ TTR P02766 1/20 0.33
▸ JAK2 O60674 1/20 0.33
▸ BTK Q06187 1/20 0.33
▸ MAPT P10636 1/20 0.32
▸ KDM4E B2RXH2 1/20 0.32
▸ ALDH1A1 P00352 1/20 0.32
▸ F11 P03951 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30774096 1.00 HSD17B10 (0.42) HSD17B10CA1CA2CA9CA12
SCHEMBL29352199 0.86 HSD17B10 (0.42) HSD17B10CA1CA2CA9CA12
SCHEMBL10269959 0.86 HSD17B10 (0.42) HSD17B10CA1CA2CA9CA12
SCHEMBL14900551 0.81 TP53 (0.38) HSD17B10LPLLIPGJAK2BTK
SCHEMBL18039553 0.80 ACHE (0.37) HSD17B10CA9CA12ESR1ESR2
SCHEMBL12481678 0.79 CYP3A4 (0.42) HSD17B10CA1CA2CA9CA12
SCHEMBL29537826 0.79 CYP3A4 (0.42) HSD17B10CA1CA2CA9CA12
SCHEMBL12496566 0.79 LPL (0.40) CA1CA2CA9ESR1ESR2
SCHEMBL3154179 0.79 LPL (0.47) CA1CA2LPLLIPGJAK2
SCHEMBL5477046 0.78 LPL (0.35) CA1CA2CA9CA12CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7507262-B2 Compositions for oxidatively dyeing keratin fibers and methods for using such compositions THE PROCTER & GAMBLE COMPANY (US) 2009-03-24 — — US claimed
EP-2018146-A2 COMPOSITIONS FOR OXIDATIVELY DYEING KERATIN FIBERS AND METHODS FOR USING SUCH COMPOSITIONS The Procter and Gamble Company (US) 2009-01-28 — — EP claimed
WO-2007102126-A2 COMPOSITIONS FOR OXIDATIVELY DYEING KERATIN FIBERS AND METHODS FOR USING SUCH COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 2007-09-13 — — WO claimed
US-20070209123-A1 Compositions for oxidatively dyeing keratin fibers and methods for using such compositions THE PROCTER & GAMBLE COMPANY 2007-09-13 — — US claimed
US-12246014-B2 Azetidine derivatives LIGAND UK DEVELOPMENT LIMITED (GB) 2025-03-11 — — US disclosed
US-20240059703-A1 HETEROCYCLIC SPIRO COMPOUNDS AND METHODS OF USE AMGEN INC. 2024-02-22 — — US disclosed
US-10918640-B2 Azetidine derivatives VERNALIS (R&D) LTD. (GB) 2021-02-16 — — US disclosed
US-10918640-B2 Azetidine derivatives VERNALIS (R&D) LTD. (GB) 2021-02-16 — — US disclosed
US-10383871-B2 Azetidine derivatives VERNALIS (R&D) LTD. (GB) 2019-08-20 — — US disclosed
US-10383871-B2 Azetidine derivatives VERNALIS (R&D) LTD. (GB) 2019-08-20 — — US disclosed
US-20170196864-A1 Azetidine Derivatives VERNALIS DEVELOPMENT LIMITED (GB) 2017-07-13 — — US disclosed
US-20170196864-A1 Azetidine Derivatives VERNALIS DEVELOPMENT LIMITED (GB) 2017-07-13 — — US disclosed
US-20090048306-A1 PYRIDINE DERIVATIVES PFIZER, INC. (US) 2009-02-19 — — US disclosed
US-20090048306-A1 PYRIDINE DERIVATIVES PFIZER, INC. (US) 2009-02-19 — — US disclosed
US-20090048306-A1 PYRIDINE DERIVATIVES PFIZER, INC. (US) 2009-02-19 — — US disclosed
EP-2018146-A2 COMPOSITIONS FOR OXIDATIVELY DYEING KERATIN FIBERS AND METHODS FOR USING SUCH COMPOSITIONS The Procter and Gamble Company (US) 2009-01-28 — — EP disclosed
WO-2008135826-A2 2 -PYRIDINE CARBOXAMIDE DERIVATIVES AS SODIUM CHANNEL MODULATORS PFIZER LIMITED (GB) 2008-11-13 — — WO disclosed
WO-2008135826-A2 2 -PYRIDINE CARBOXAMIDE DERIVATIVES AS SODIUM CHANNEL MODULATORS PFIZER LIMITED (GB) 2008-11-13 — — WO disclosed
WO-2007102126-A2 COMPOSITIONS FOR OXIDATIVELY DYEING KERATIN FIBERS AND METHODS FOR USING SUCH COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 2007-09-13 — — WO disclosed
US-20070209123-A1 Compositions for oxidatively dyeing keratin fibers and methods for using such compositions THE PROCTER & GAMBLE COMPANY 2007-09-13 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10918640-B2 Azetidine derivatives FAAH2, FAAH, APEH HSD17B10 394/4885CA1 3828/4885CA2 3255/4885
US-12246014-B2 Azetidine derivatives FAAH2, FAAH, APEH HSD17B10 365/4885CA1 3765/4885CA2 3348/4885
US-20170196864-A1 Azetidine Derivatives FAAH2, FAAH, APEH HSD17B10 394/4885CA1 3828/4885CA2 3255/4885
US-20240059703-A1 HETEROCYCLIC SPIRO COMPOUNDS AND METHODS OF USE KRAS, HRAS, APC HSD17B10 2525/4885CA1 2690/4885CA2 2804/4885
US-20090048306-A1 PYRIDINE DERIVATIVES SDHA, P2RX4, P2RX3 HSD17B10 1795/4885CA1 3204/4885CA2 1236/4885
US-10383871-B2 Azetidine derivatives FAAH2, FAAH, APEH HSD17B10 394/4885CA1 3828/4885CA2 3255/4885
US-20070209123-A1 Compositions for oxidatively dyeing keratin fibers and methods for using such compositions KRT18, AKR7A2, AKR1C4 HSD17B10 1179/4885CA1 1171/4885CA2 1153/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.