Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | KLKB1 | P03952 | 8/20 | 0.37 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.35 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.34 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.34 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.34 |
| ▸ | MPO | P05164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17067013 | 0.84 | L3MBTL1 (0.40) | LMNAPOLBGAAKLKB1GRM2 | |
| SCHEMBL26406052 | 0.83 | ADORA3 (0.38) | LMNAADORA3KLKB1ADRA1D | |
| SCHEMBL26406187 | 0.83 | ADORA3 (0.41) | LMNAADORA3KLKB1ADRA1D | |
| SCHEMBL26135704 | 0.79 | ADORA3 (0.36) | ADORA3KLKB1ADRA1D | |
| SCHEMBL970933 | 0.79 | GAA (0.55) | LMNAPOLBGAASTING1 | |
| SCHEMBL26420237 | 0.78 | AR (0.36) | ADORA3ADRA1D | |
| SCHEMBL21408586 | 0.76 | LMNA (0.39) | LMNAPOLBGAAKLKB1DGAT1 | |
| SCHEMBL23212135 | 0.75 | PARP1 (0.56) | KLKB1DGAT1 | |
| SCHEMBL26425850 | 0.75 | LMNA (0.40) | LMNAPOLBKLKB1DGAT1 | |
| SCHEMBL20521837 | 0.73 | GAA (0.53) | GAAKLKB1GRM2DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023192901-A9 | QUINOLINE DERIVATIVES AS MODULATORS OF MAS-RELATED G-PROTEIN RECEPTOR X2 AND RELATED PRODUCTS | ESCIENT PHARMACEUTICALS, INC. (US) | 2023-12-14 | — | — | WO | disclosed |
| WO-2023192901-A1 | QUINOLINE DERIVATIVES AS MODULATORS OF MAS-RELATED G-PROTEIN RECEPTOR X2 AND RELATED PRODUCTS | ESCIENT PHARMACEUTICALS, INC. (US) | 2023-10-05 | — | — | WO | disclosed |