Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 7/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 8/20 | 0.33 |
| ▸ | JAK1 | P23458 | 8/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28309161 | 0.81 | JAK3 (0.41) | JAK2JAK1PARP1 | |
| SCHEMBL26406052 | 0.80 | ADORA3 (0.38) | ADORA3ADRA1DJAK1PARP1 | |
| SCHEMBL26406187 | 0.80 | ADORA3 (0.41) | ADORA3ADRA1DJAK2JAK1PARP1 | |
| SCHEMBL26419960 | 0.78 | LMNA (0.39) | ADORA3ADRA1D | |
| SCHEMBL30621006 | 0.77 | TGFBR1 (0.36) | JAK2JAK1PARP1 | |
| SCHEMBL26135704 | 0.76 | ADORA3 (0.36) | ADORA3ADRA1DPARP1 | |
| SCHEMBL26419133 | 0.76 | ADORA2A (0.37) | JAK2JAK1PARP1 | |
| SCHEMBL31253880 | 0.69 | ROCK2 (0.36) | JAK2JAK1 | |
| SCHEMBL22262871 | 0.67 | KLKB1 (0.48) | ADRA1DPARP1 | |
| SCHEMBL20531574 | 0.67 | KLKB1 (0.49) | JAK2JAK1PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119095839-A | Quinoline derivatives as modulators and related products of Mas-associated G protein receptor X2 | 伊赛恩特制药公司 | 2024-12-06 | — | — | CN | disclosed |
| WO-2023192901-A9 | QUINOLINE DERIVATIVES AS MODULATORS OF MAS-RELATED G-PROTEIN RECEPTOR X2 AND RELATED PRODUCTS | ESCIENT PHARMACEUTICALS, INC. (US) | 2023-12-14 | — | — | WO | disclosed |
| WO-2023192901-A1 | QUINOLINE DERIVATIVES AS MODULATORS OF MAS-RELATED G-PROTEIN RECEPTOR X2 AND RELATED PRODUCTS | ESCIENT PHARMACEUTICALS, INC. (US) | 2023-10-05 | — | — | WO | disclosed |