SCHEMBL264365

SCHEMBL264365

Fc1ncnc2nc[nH]c12

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PI4KA P42356 2/20 0.57
PI4K2B Q8TCG2 2/20 0.57
PI4K2A Q9BTU6 2/20 0.57
PI4KB Q9UBF8 2/20 0.57
LRRK2 Q5S007 2/20 0.57
LMNA P02545 2/20 0.57
DRD3 P35462 1/20 0.57
XDH P47989 1/20 0.57
G6PD P11413 1/20 0.55
PDPK1 O15530 3/20 0.52
TP53 P04637 2/20 0.52
CHEK1 O14757 2/20 0.52
AURKA O14965 1/20 0.52
CHEK2 O96017 1/20 0.52
HSP90AA1 P07900 1/20 0.52
HSP90AB1 P08238 1/20 0.52
PRKACA P17612 1/20 0.52
CCNE1 P24864 1/20 0.52
CDK2 P24941 1/20 0.52
MARK3 P27448 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29724676 0.73 LMNA (0.57) PI4KAPI4K2BPI4K2API4KBLRRK2
SCHEMBL2008437 0.73 LMNA (0.57) PI4KAPI4K2BPI4K2API4KBLRRK2
SCHEMBL375936 0.73 LRRK2 (0.57) PI4KAPI4K2BPI4K2API4KBLRRK2
Adenine SCHEMBL1331751 0.73 PI4KA (1.00) PI4KAPI4K2BPI4K2API4KBLRRK2
SCHEMBL11491986 0.73 LMNA (0.57) PI4KAPI4K2BPI4K2API4KBLRRK2
Adenine SCHEMBL8111 0.73 PI4KA (1.00) PI4KAPI4K2BPI4K2API4KBLRRK2
SCHEMBL532632 0.73 PI4KA (0.57) PI4KAPI4K2BPI4K2API4KBLRRK2
Mercaptopurine Anhydrous SCHEMBL8844 0.73 LMNA (0.57) PI4KAPI4K2BPI4K2API4KBLRRK2
Adenine SCHEMBL3414606 0.73 PI4KA (1.00) PI4KAPI4K2BPI4K2API4KBLRRK2
SCHEMBL275945 0.73 LMNA (0.57) PI4KAPI4K2BPI4K2API4KBLRRK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 203 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4717779-A2 COMPOSITIONS AND METHODS FOR SYNTHESIZING 5'-CAPPED RNAS TriLink BioTechnologies, LLC (US) 2026-04-01 EP claimed
CN-118931997-A Method for synthesizing adenosine and/or uridine by three-enzyme cascade catalysis 上海飞腾医药科技有限公司 2024-11-12 CN claimed
US-7265111-B2 Adenosine analogues and their use as pharmaceutical agents SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) 2007-09-04 US claimed
CN-1671728-A Novel adenosine analogues and their use as pharmaceutical agents AVENTIS PHARMA GMBH (DE) 2005-09-21 CN claimed
EP-1527083-A1 NOVEL ADENOSINE ANALOGUES AND THEIR USE AS PHARMACEUTICAL AGENTS Aventis Pharma Deutschland GmbH (DE) 2005-05-04 EP claimed
US-20040127434-A1 Novel adenosine analogues and their use as pharmaceutical agents SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) 2004-07-01 US claimed
WO-2004003002-A1 NOVEL ADENOSINE ANALOGUES AND THEIR USE AS PHARMACEUTICAL AGENTS AVENTIS PHARMA DEUTSCHLAND GMBH (DE) 2004-01-08 WO claimed
EP-1375508-A1 N6-substituted adenosine analogues and their use as pharmaceutical agents Aventis Pharma Deutschland GmbH (DE) 2004-01-02 EP claimed
CN-1117870-C Method for producing nucleoside-5' -phosphate ester AJINOMOTO KK (JP) 2003-08-13 CN claimed
US-5817799-A 2'-Fluorofuranosyl derivatives and methods for preparing 2'-fluoropyrimidine and 2'-fluoropurine nucleosides THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 1998-10-06 US claimed
EP-0540686-B1 2'-FLUOROFURANOSYL DERIVATIVES AND NOVEL METHOD OF PREPARING 2'-FLUOROPYRIMIDINE AND 2'-FLUOROPURINE NUCLEOSIDES US COMMERCE (US) 1995-08-30 EP claimed
EP-0540686-A4 2'-FLUOROFURANOSYL DERIVATIVES AND NOVEL METHOD OF PREPARING 2'-FLUOROPYRIMIDINE AND 2'-FLUOROPURINE NUCLEOSIDES US COMMERCE (US) 1993-05-26 EP claimed
EP-0540686-A1 2'-FLUOROFURANOSYL DERIVATIVES AND NOVEL METHOD OF PREPARING 2'-FLUOROPYRIMIDINE AND 2'-FLUOROPURINE NUCLEOSIDES. US COMMERCE (US) 1993-05-12 EP claimed
WO-1992001700-A1 2'-FLUOROFURANOSYL DERIVATIVES AND NOVEL METHOD OF PREPARING 2'-FLUOROPYRIMIDINE AND 2'-FLUOROPURINE NUCLEOSIDES THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, U.S. DEPARTMENT OF COMMERCE (US) 1992-02-06 WO claimed
JP-3076594-A None JP disclosed
US-20260109977-A1 MODIFIED RNA FOR INCREASING PROTEIN EXPRESSION TRILINK BIOTECHNOLOGIES, LLC (US) 2026-04-23 US disclosed
EP-4276189-B1 INITIATING CAPPED OLIGONUCLEOTIDE PRIMERS FOR SYNTHESIZING 5'-CAPPED RNAS TRILINK BIOTECHNOLOGIES LLC (US) 2026-04-01 EP disclosed
WO-1991012260-A1 6-HALO- AND 2-AMINO-6-HALO-PURINE 2',3'-DIDEOXY NUCLEOSIDES AND THEIR USE AS ANTIVIRAL AGENTS THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, U.S. DEPARTMENT OF COMMERCE (US) 1991-08-22 WO disclosed
JP-H0376594-A PRODUCTION OF DIDEOXYNUCLEOTIDE DERIVATIVE AJINOMOTO CO INC 1991-04-02 JP disclosed
JP-H00376594-A 0001-01-01 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260109977-A1 MODIFIED RNA FOR INCREASING PROTEIN EXPRESSION RNGTT, RNMT, UPF1 PI4KA 4241/4885PI4K2B 3370/4885PI4K2A 3707/4885
US-20040127434-A1 Novel adenosine analogues and their use as pharmaceutical agents ADORA1, ADORA2A, ADORA2B PI4KA 845/4885PI4K2B 504/4885PI4K2A 480/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.