Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PCSK9 | Q8NBP7 | 2/20 | 0.42 |
| ▸ | ORAI1 | Q96D31 | 3/20 | 0.41 |
| ▸ | ORAI2 | Q96SN7 | 3/20 | 0.41 |
| ▸ | ORAI3 | Q9BRQ5 | 3/20 | 0.41 |
| ▸ | TRPV6 | Q9H1D0 | 3/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA6 | P23280 | 1/20 | 0.41 |
| ▸ | CA5A | P35218 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | LTA4H | P09960 | 1/20 | 0.32 |
| ▸ | MGLL | Q99685 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3983901 | 0.84 | PCSK9 (0.44) | PCSK9ORAI1ORAI2ORAI3TRPV6 | |
| SCHEMBL2140994 | 0.82 | LPL (0.46) | ORAI1ORAI2ORAI3TRPV6CA1 | |
| SCHEMBL16515982 | 0.81 | PCSK9 (0.50) | PCSK9ORAI1ORAI2ORAI3TRPV6 | |
| SCHEMBL3654165 | 0.80 | ENPP2 (0.38) | PCSK9ORAI1ORAI2ORAI3TRPV6 | |
| SCHEMBL20561442 | 0.80 | PCSK9 (0.37) | PCSK9ORAI1ORAI2ORAI3TRPV6 | |
| SCHEMBL3411767 | 0.79 | TSHR (0.38) | PCSK9ORAI1ORAI2ORAI3TRPV6 | |
| SCHEMBL19893832 | 0.79 | LMNA (0.40) | PCSK9ORAI1ORAI2ORAI3TRPV6 | |
| SCHEMBL1722636 | 0.78 | PCSK9 (0.45) | PCSK9ORAI1ORAI2ORAI3TRPV6 | |
| SCHEMBL28369729 | 0.78 | ORAI1 (0.37) | PCSK9ORAI1ORAI2ORAI3TRPV6 | |
| SCHEMBL3984743 | 0.78 | ACHE (0.38) | ENPP2MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113621215-B | Preparation method of organic-inorganic hybrid biomass phenolic resin ablation-resistant material | 哈尔滨工业大学 | 2024-02-09 | — | — | CN | claimed |
| CN-113621215-A | Preparation method of organic-inorganic hybrid biomass phenolic resin ablation-resistant material | 哈尔滨工业大学 | 2021-11-09 | — | — | CN | claimed |
| CN-111171721-B | Ceramizable ablation-resistant coating and preparation method thereof | 西安近代化学研究所 | 2021-08-20 | — | — | CN | claimed |
| CN-111171721-A | Ceramizable ablation-resistant coating and preparation method thereof | 西安近代化学研究所 | 2020-05-19 | — | — | CN | claimed |
| CN-119708891-A | Organic silicon oligomer intercalated montmorillonite, preparation method thereof, modified hot melt boron phenolic resin and preparation method thereof | 西安交通大学 | 2025-03-28 | — | — | CN | disclosed |
| US-20240296914-A1 | UV-VIS SPECTRA PREDICTION | COLLABORATIONS PHARMACEUTICALS, INC. (US) | 2024-09-05 | — | — | US | disclosed |
| CN-117903387-A | Low-free aldehyde hot-melt boron phenolic resin and preparation method thereof | 西安交通大学 | 2024-04-19 | — | — | CN | disclosed |
| WO-2023239811-A1 | SUBSTITUTED BIARYL ENDOCHIN-LIKE QUINOLONES WITH ENHANCED ANTIPARASITIC ACTIVITY | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2023-12-14 | — | — | WO | disclosed |
| US-20230181462-A1 | Dynamic Covalent Hydrogels, Precursors Thereof and Uses Thereof | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2023-06-15 | — | — | US | disclosed |
| CN-115812085-A | Dynamic covalent hydrogels, precursors thereof and uses thereof | 国家科学研究中心 | 2023-03-17 | — | — | CN | disclosed |
| EP-4118136-A1 | DYNAMIC COVALENT HYDROGELS, PRECURSORS THEREOF AND USES THEREOF | Centre National de la Recherche Scientifique (CNRS) (FR) | 2023-01-18 | — | — | EP | disclosed |
| CN-113621215-A | Preparation method of organic-inorganic hybrid biomass phenolic resin ablation-resistant material | 哈尔滨工业大学 | 2021-11-09 | — | — | CN | disclosed |
| EP-2205548-A1 | SUBSTITUTED BIPHENYL GPR40 MODULATORS | Amgen, Inc (US) | 2010-07-14 | — | — | EP | disclosed |
| WO-2009109483-A1 | LEUKOTRIENE B4 INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2009-09-11 | — | — | WO | disclosed |
| WO-2009048527-A1 | SUBSTITUTED BIPHENYL GPR40 MODULATORS | AMGEN INC. (US) | 2009-04-16 | — | — | WO | disclosed |
| US-20090048306-A1 | PYRIDINE DERIVATIVES | PFIZER, INC. (US) | 2009-02-19 | — | — | US | disclosed |
| EP-1899332-A1 | PYRIDO(3,2-D)PYRIMIDINES AND PHARMACEUTICAL COMPOSITIONS USEFUL FOR TREATING HEPATITIS C. | GILEAD SCIENCES, INC. (US) | 2008-03-19 | — | — | EP | disclosed |
| WO-2006135993-A1 | PYRIDO(3,2-D)PYRIMIDINES AND PHARMACEUTICAL COMPOSITIONS USEFUL FOR TREATING HEPATITIS C. | GILEAD SCIENCES, INC. (US) | 2006-12-28 | — | — | WO | disclosed |
| EP-0708769-A1 | SUBSTITUTED 2-FUSED PHENYLPYRIDINES WITH HERBICIDAL ACTIVITY | BASF AKTIENGESELLSCHAFT (DE) | 1996-05-01 | — | — | EP | disclosed |
| WO-1995002590-A2 | SUBSTITUTED 2-FUSED PHENYLPYRIDINES WITH HERBICIDAL ACTIVITIES | BASF AKTIENGESELLSCHAFT (DE) | 1995-01-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090048306-A1 | PYRIDINE DERIVATIVES | SDHA, P2RX4, P2RX3 | PCSK9 2872/4885ORAI1 1050/4885ORAI2 2089/4885 |
| US-20230181462-A1 | Dynamic Covalent Hydrogels, Precursors Thereof and Uses Thereof | CDC37, ILK, PTMS | PCSK9 4023/4885ORAI1 4159/4885ORAI2 4627/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.