Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.48 |
| ▸ | MAOB | P27338 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | PARP1 | P09874 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7990104 | 0.84 | MAOA (0.56) | MAOAMAOBMAPTL3MBTL1TDP1 | |
| SCHEMBL3383700 | 0.83 | NR4A2 (0.61) | MAOAMAOBMAPTL3MBTL1TDP1 | |
| SCHEMBL27579430 | 0.81 | MAOA (0.55) | MAOAMAOBMAPTL3MBTL1TDP1 | |
| SCHEMBL14565162 | 0.79 | ALDH1A1 (0.50) | MAOAMAOBMAPTL3MBTL1TDP1 | |
| SCHEMBL5924614 | 0.79 | ALDH1A1 (0.44) | MAOAMAOBMAPTL3MBTL1TDP1 | |
| SCHEMBL660788 | 0.78 | NR4A2 (0.68) | MAPTL3MBTL1TDP1POLBCYP3A4 | |
| SCHEMBL1536703 | 0.78 | MAOA (0.56) | MAOAMAOBMAPTPOLBALDH1A1 | |
| SCHEMBL29166026 | 0.76 | NR4A2 (0.53) | MAOAMAOBMAPTL3MBTL1TDP1 | |
| SCHEMBL7855197 | 0.76 | MAOA (0.48) | MAOAMAOBMAPTL3MBTL1TDP1 | |
| SCHEMBL3661482 | 0.75 | L3MBTL1 (0.48) | MAPTL3MBTL1TDP1POLBCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3507275-B1 | CXCR3 RECEPTOR AGONISTS | RECEPTOS LLC (US) | 2023-04-26 | — | — | EP | disclosed |