Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOD1 | Q9Y239 | 6/20 | 0.48 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.47 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.47 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.47 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.47 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | LCK | P06239 | 1/20 | 0.44 |
| ▸ | PPARD | Q03181 | 1/20 | 0.44 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.44 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.44 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.43 |
| ▸ | ACE | P12821 | 3/20 | 0.42 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7262078 | 0.90 | SLC6A5 (0.49) | NOD1GRIK1GRIK2SLC1A2SLC1A1 | |
| SCHEMBL11220090 | 0.84 | GPR84 (0.57) | NOD1GRIK1GRIK2GPR84FFAR1 | |
| SCHEMBL17024089 | 0.84 | GPR84 (0.57) | NOD1GRIK1GRIK2GPR84FFAR1 | |
| SCHEMBL6152930 | 0.81 | GSR (0.52) | SLC6A5ACE | |
| SCHEMBL6238817 | 0.80 | CA2 (0.52) | NOD1SLC1A2SLC1A1GPR84FFAR1 | |
| SCHEMBL16948271 | 0.79 | GNPAT (0.51) | NOD1GRIK1GRIK2SLC1A2SLC1A1 | |
| SCHEMBL7568291 | 0.78 | GPR84 (0.50) | NOD1GPR84FFAR1MAPTLCK | |
| SCHEMBL721340 | 0.77 | OPRM1 (0.55) | GRIK1GRIK2SLC1A2SLC1A1MAPT | |
| SCHEMBL28754574 | 0.77 | GPR84 (0.53) | NOD1GRIK1GRIK2SLC1A2SLC1A1 | |
| SCHEMBL21059255 | 0.76 | NOD1 (0.49) | NOD1GPR84FFAR1MAPTLCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2263087-B1 | LABELED REACTANTS AND THEIR USES | PACIFIC BIOSCIENCES CALIFORNIA INC (US) | 2017-08-09 | — | — | EP | disclosed |
| US-9587275-B2 | Single molecule sequencing with two distinct chemistry steps | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2017-03-07 | — | — | US | disclosed |
| US-9464107-B2 | Labeled nucleotide analogs | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2016-10-11 | — | — | US | disclosed |
| US-9447464-B2 | Single molecule sequencing with two distinct chemistry steps | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2016-09-20 | — | — | US | disclosed |
| US-20160010150-A1 | SINGLE MOLECULE SEQUENCING WITH TWO DISTINCT CHEMISTRY STEPS | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. | 2016-01-14 | — | — | US | disclosed |
| US-8906614-B2 | Labeled reactants and their uses | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2014-12-09 | — | — | US | disclosed |
| US-20140186825-A1 | LABELED NUCLEOTIDE ANALOGS | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2014-07-03 | — | — | US | disclosed |
| US-20140127680-A1 | SINGLE MOLECULE SEQUENCING WITH TWO DISTINCT CHEMISTRY STEPS | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2014-05-08 | — | — | US | disclosed |
| US-8603741-B2 | Single molecule sequencing with two distinct chemistry steps | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2013-12-10 | — | — | US | disclosed |
| US-20130183663-A1 | LABELED REACTANTS AND THEIR USES | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2013-07-18 | — | — | US | disclosed |
| US-8133702-B2 | Engineered fluorescent dye labeled nucleotide analogs for DNA sequencing | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2012-03-13 | — | — | US | disclosed |
| US-20120028248-A1 | ENGINEERED FLUORESCENT DYE LABELED NUCLEOTIDE ANALOGS FOR DNA SEQUENCING | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2012-02-02 | — | — | US | disclosed |
| US-20110311964-A1 | LABELED REACTANTS AND THEIR USES | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2011-12-22 | — | — | US | disclosed |
| US-20110212437-A1 | SINGLE MOLECULE SEQUENCING WITH TWO DISTINCT CHEMISTRY STEPS | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2011-09-01 | — | — | US | disclosed |
| US-7973146-B2 | Engineered fluorescent dye labeled nucleotide analogs for DNA sequencing | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2011-07-05 | — | — | US | disclosed |
| US-7968702-B2 | Labeled reactants and their uses | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2011-06-28 | — | — | US | disclosed |
| EP-2263087-A1 | LABELED REACTANTS AND THEIR USES | Pacific Biosciences of California, Inc. (US) | 2010-12-22 | — | — | EP | disclosed |
| US-20090246791-A1 | ENGINEERED FLUORESCENT DYE LABELED NUCLEOTIDE ANALOGS FOR DNA SEQUENCING | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2009-10-01 | — | — | US | disclosed |
| US-20090233302-A1 | LABELED REACTANTS AND THEIR USES | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2009-09-17 | — | — | US | disclosed |
| WO-2009114182-A1 | LABELED REACTANTS AND THEIR USES | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2009-09-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110212437-A1 | SINGLE MOLECULE SEQUENCING WITH TWO DISTINCT CHEMISTRY STEPS | RNGTT, POLL, NUDT21 | NOD1 1512/4885GRIK1 4351/4885GRIK2 4507/4885 |
| US-20090246791-A1 | ENGINEERED FLUORESCENT DYE LABELED NUCLEOTIDE ANALOGS FOR DNA SEQUENCING | POLM, POLN, POLB | NOD1 1304/4885GRIK1 4437/4885GRIK2 4602/4885 |
| US-20120028248-A1 | ENGINEERED FLUORESCENT DYE LABELED NUCLEOTIDE ANALOGS FOR DNA SEQUENCING | POLN, POLM, RNGTT | NOD1 1034/4885GRIK1 4315/4885GRIK2 4529/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.