Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 3/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | TNNI3K | Q59H18 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 4/20 | 0.43 |
| ▸ | CA1 | P00915 | 3/20 | 0.43 |
| ▸ | MMP1 | P03956 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | MMP8 | P22894 | 1/20 | 0.43 |
| ▸ | MMP13 | P45452 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5181504 | 0.83 | LMNA (0.53) | ACHEHDAC8HDAC4HDAC2HDAC3 | |
| SCHEMBL798087 | 0.82 | KIF11 (0.50) | ACHEHDAC8HDAC4HDAC2HDAC3 | |
| SCHEMBL4616498 | 0.82 | CA1 (0.62) | CA2CA1MMP1MMP2MMP9 | |
| SCHEMBL10145039 | 0.81 | ACHE (0.50) | ACHEHDAC8HDAC4HDAC2HDAC3 | |
| SCHEMBL10145034 | 0.81 | RAB9A (0.51) | ACHEHDAC8HDAC4HDAC2HDAC3 | |
| SCHEMBL12025007 | 0.80 | CA2 (0.61) | HDAC8HDAC4HDAC2CA2CA1 | |
| SCHEMBL31678755 | 0.80 | ALDH1A1 (0.52) | ACHEHDAC8HDAC4HDAC2HDAC3 | |
| SCHEMBL2217011 | 0.80 | ALDH1A1 (0.46) | ACHEHDAC8HDAC4HDAC2HDAC3 | |
| SCHEMBL7427764 | 0.80 | ALDH1A1 (0.52) | ACHEHDAC8HDAC4HDAC2HDAC3 | |
| SCHEMBL10034524 | 0.80 | ALDH1A1 (0.59) | ACHEHDAC8HDAC4HDAC2HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117051414-A | Method for electrochemically synthesizing aryl sulfonyl fluoride compound | 常州工学院 | 2023-11-14 | — | — | CN | claimed |
| CN-117051414-A | Method for electrochemically synthesizing aryl sulfonyl fluoride compound | 常州工学院 | 2023-11-14 | — | — | CN | disclosed |
| US-20230331721-A1 | POTENT AND SELECTIVE COVALENT INHIBITORS OF SERINE-ARGININE PROTEIN KINASE (SRPK) 1 AND SRPK2 AND USES THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2023-10-19 | — | — | US | disclosed |
| US-20230331721-A1 | POTENT AND SELECTIVE COVALENT INHIBITORS OF SERINE-ARGININE PROTEIN KINASE (SRPK) 1 AND SRPK2 AND USES THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2023-10-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230331721-A1 | POTENT AND SELECTIVE COVALENT INHIBITORS OF SERINE-ARGININE PROTEIN KINASE (SRPK) 1 AND SRPK2 AND USES THEREOF | SRPK1, SRPK2, SRPK3 | ACHE 4283/4885HDAC8 2054/4885HDAC4 2855/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.