Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | DRD2 | P14416 | 2/20 | 0.55 |
| ▸ | DRD1 | P21728 | 2/20 | 0.55 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.55 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.55 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.55 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
| ▸ | DRD4 | P21917 | 1/20 | 0.50 |
| ▸ | DRD5 | P21918 | 1/20 | 0.50 |
| ▸ | DRD3 | P35462 | 1/20 | 0.50 |
| ▸ | SPR | P35270 | 1/20 | 0.50 |
| ▸ | IDO1 | P14902 | 1/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.49 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.49 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.49 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.49 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.49 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.49 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19932503 | 0.89 | HDAC6 (0.58) | ALDH1A1DRD2DRD1TAAR1CHRM2 | |
| SCHEMBL18768957 | 0.88 | ALDH1A1 (0.72) | ALDH1A1IAPPKDM4ENPC1LMNA | |
| SCHEMBL14935497 | 0.87 | HDAC6 (0.65) | ALDH1A1DRD2DRD1TAAR1CHRM2 | |
| SCHEMBL30692614 | 0.84 | DRD2 (0.59) | DRD2DRD1TAAR1CHRM2CHRM1 | |
| SCHEMBL29822763 | 0.84 | DRD2 (0.59) | DRD2DRD1TAAR1CHRM2CHRM1 | |
| SCHEMBL11756870 | 0.84 | DRD2 (0.59) | DRD2DRD1TAAR1CHRM2CHRM1 | |
| SCHEMBL65250 | 0.82 | KEAP1 (0.63) | DRD2DRD1TAAR1CHRM2CHRM1 | |
| SCHEMBL29563859 | 0.82 | KEAP1 (0.63) | DRD2DRD1TAAR1CHRM2CHRM1 | |
| SCHEMBL31336237 | 0.82 | KEAP1 (0.63) | DRD2DRD1TAAR1CHRM2CHRM1 | |
| Benzylacetone SCHEMBL27760585 | 0.82 | ALDH1A1 (0.84) | ALDH1A1HDAC6KDM4EMAPTSLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1882307-A | Method for dyeing fibres containing keratine | HENKEL KGAA (DE) | 2006-12-20 | — | — | CN | claimed |
| US-11746364-B2 | Enzymatic synthesis of kavalactones and flavokavains | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH (US) | 2023-09-05 | — | — | US | disclosed |
| US-11739354-B2 | Enzymatic synthesis of kavalactones and flavokavains | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH (US) | 2023-08-29 | — | — | US | disclosed |
| US-11034725-B2 | Compositions and methods for treating cardiovascular disease | GENENTECH, INC. (US) | 2021-06-15 | — | — | US | disclosed |
| US-20200283478-A1 | COMPOSITIONS AND METHODS FOR TREATING CARDIOVASCULAR DISEASE | GENENTECH, INC. (US) | 2020-09-10 | — | — | US | disclosed |
| US-20190041765-A1 | ELECTROPHOTOGRAPHIC INK INCLUDING A VOLATILE FRAGRANCE | HP INDIGO B.V. (NL) | 2019-02-07 | — | — | US | disclosed |
| CN-109265330-A | A kind of preparation method of 4-(4-hydroxyphenyl)-2-butanone | 广州中大南沙科技创新产业园有限公司 | 2019-01-25 | — | — | CN | disclosed |
| CN-108530280-A | The method of acid immobilized ionic liquid-catalyzed synthesis raspberry ketone | 浙江工业大学 | 2018-09-14 | — | — | CN | disclosed |
| WO-2017152964-A1 | ELECTROPHOTOGRAPHIC INK INCLUDING A VOLATILE FRAGRANCE | HP INDIGO B.V. (NL) | 2017-09-14 | — | — | WO | disclosed |
| US-20170210734-A1 | Substituted Azaspiro(4.5)Decane Derivatives | GRUENENTHAL GMBH (DE) | 2017-07-27 | — | — | US | disclosed |
| EP-1133476-A1 | IMINOGUANIDINE DERIVATIVES, PREPARATION METHOD, USE AS MEDICINES | Aventis Pharma S.A. (FR) | 2001-09-19 | — | — | EP | disclosed |
| WO-2000031044-A1 | IMINOGUANIDINE DERIVATIVES, PREPARATION METHOD, USE AS MEDICINES | AVENTIS PHARMA S.A. (FR) | 2000-06-02 | — | — | WO | disclosed |
| WO-2000015617-A1 | 2-AMINOETHYL-QUINOLINE DERIVATIVES, PREPARATION AND THERAPEUTIC USE | SANOFI-SYNTHELABO (FR) | 2000-03-23 | — | — | WO | disclosed |
| CN-1230096-A | Chewing gum with extended and improved flavor containing dipeptide sweetener | HOLLAND SWEETENER CO (NL) | 1999-09-29 | — | — | CN | disclosed |
| US-5763368-A | AQUEOUS SOLUTION OF QUATERNARY AMMONIUM COMPOUND AND INTENSIFIER | HALLIBURTON ENERGY SERVICES, INC. (US) | 1998-06-09 | — | — | US | disclosed |
| US-5097375-A | CONTAINER WITH RECORDING MEDIUM AND HAVING A FRAGRANCE EMITTING MATERIAL | BASF AKTIENGESELLSCHAFT (DE) | 1992-03-17 | — | — | US | disclosed |
| US-5097376-A | CONTAINER WITH RECORDING MEDIUM HAVING FRAGRANCE MATERIAL IN OR ON THE RECORDING MEDIUM | BASF AKTIENGESELLSCHAFT (DE) | 1992-03-17 | — | — | US | disclosed |
| EP-0386584-A1 | Container with data carrier | BASF Aktiengesellschaft (DE) | 1990-09-12 | — | — | EP | disclosed |
| US-4309422-A | INSECTICIDES | VELSICOL CHEMICAL CORPORATION (US) | 1982-01-05 | — | — | US | disclosed |
| EP-0007205-A1 | Optically active phenethanolamines, their formulations, use and preparation | ELI LILLY AND COMPANY (US) | 1980-01-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200283478-A1 | COMPOSITIONS AND METHODS FOR TREATING CARDIOVASCULAR DISEASE | PCSK9, PCSK7, PCSK6 | ALDH1A1 4023/4885DRD2 4852/4885DRD1 4870/4885 |
| US-20170210734-A1 | Substituted Azaspiro(4.5)Decane Derivatives | OPRL1, OPRM1, OPRD1 | ALDH1A1 359/4885DRD2 414/4885DRD1 236/4885 |
| US-11034725-B2 | Compositions and methods for treating cardiovascular disease | PCSK9, PCSK7, PCSK6 | ALDH1A1 4023/4885DRD2 4852/4885DRD1 4870/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.