Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G7 | Q13093 | 3/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2660852 | 0.93 | PLA2G7 (0.33) | PLA2G7MEN1MAPTKMT2AMCL1 | |
| SCHEMBL2660397 | 0.89 | MCL1 (0.31) | MCL1 | |
| SCHEMBL2660809 | 0.87 | PLA2G7 (0.33) | PLA2G7MCL1LMNAPOLB | |
| SCHEMBL2661327 | 0.85 | PLA2G7 (0.31) | PLA2G7MEN1KMT2ALMNAPOLB | |
| SCHEMBL2659767 | 0.82 | PYGL (0.32) | MEN1MAPTKMT2AMCL1LMNA | |
| SCHEMBL2660563 | 0.82 | HDAC3 (0.36) | PLA2G7MAPT | |
| SCHEMBL2660524 | 0.81 | RAB9A (0.35) | MEN1MAPTKMT2AMCL1LMNA | |
| SCHEMBL2977084 | 0.79 | TP53 (0.34) | MEN1MAPTKMT2ALMNAPOLB | |
| SCHEMBL2659747 | 0.77 | MCL1 (0.31) | MCL1 | |
| SCHEMBL2659987 | 0.76 | LGALS8 (0.33) | KMT2AMCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2074119-A1 | INDOLE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2009-07-01 | — | — | EP | disclosed |
| WO-2008050821-A1 | INDOLE COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-05-02 | — | — | WO | disclosed |