(Phenylamino)Acetonitrile

(Phenylamino)Acetonitrile

SCHEMBL26699804

N#CCNc1ccccc1.[NaH]

nearest known ligand 0.46

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.46
MAPT P10636 2/20 0.46
CDK1 P06493 1/20 0.45
CDK2 P24941 1/20 0.45
CA2 P00918 2/20 0.43
CA9 Q16790 2/20 0.43
GRM5 P41594 1/20 0.41
TSHR P16473 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
MEN1 O00255 1/20 0.38
CYP1A2 P05177 1/20 0.38
CYP3A4 P08684 1/20 0.38
CYP2C9 P11712 1/20 0.38
CYP2C19 P33261 1/20 0.38
KMT2A Q03164 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
HTT P42858 1/20 0.38
CTSD P07339 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
CA12 O43570 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
(Phenylamino)Acetonitrile SCHEMBL197012 0.98 ALDH1A1 (0.48) ALDH1A1MAPTCDK1CDK2CA2
(Phenylamino)Acetonitrile SCHEMBL7717385 0.95 MAPT (0.46) ALDH1A1MAPTCDK1CDK2CA2
(Phenylamino)Acetonitrile SCHEMBL10944153 0.82 ALDH1A1 (0.50) ALDH1A1MAPTTSHRL3MBTL1MEN1
(Phenylamino)Acetonitrile SCHEMBL4430710 0.82 PKM (0.43) ALDH1A1MAPTCDK1CDK2CA2
SCHEMBL5250150 0.80 LMNA (0.50) ALDH1A1MAPTTSHRMEN1KMT2A
SCHEMBL10997472 0.77 GRM5 (0.53) ALDH1A1MAPTCA2CA9GRM5
SCHEMBL8395286 0.76 MAPT (0.58) ALDH1A1MAPTCA2CA9L3MBTL1
SCHEMBL7573615 0.76 CA2 (0.43) ALDH1A1MAPTCDK1CDK2CA2
SCHEMBL28924232 0.76 LMNA (0.48) ALDH1A1MAPTCDK1CDK2TSHR
SCHEMBL728548 0.75 MAPT (0.41) ALDH1A1MAPTCDK1CDK2CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023226263-A1 ANILINOACETATE AND SYNTHESIS METHOD THEREFOR 上海东庚化工技术有限公司 2023-11-30 WO disclosed