(Phenylamino)Acetonitrile

(Phenylamino)Acetonitrile

SCHEMBL10944153

N#CCNc1ccccc1.N#Cc1cccc(C#N)c1

nearest known ligand 0.50

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.50
MAPT P10636 3/20 0.50
LMNA P02545 2/20 0.48
KCNA5 P22460 1/20 0.47
TSHR P16473 2/20 0.45
HSD17B10 Q99714 2/20 0.44
MAPK1 P28482 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
HTT P42858 1/20 0.44
ADORA2B P29275 2/20 0.43
ADORA1 P30542 2/20 0.43
ADORA2A P29274 1/20 0.43
ABCG2 Q9UNQ0 1/20 0.43
KDM4E B2RXH2 2/20 0.42
GAA P10253 1/20 0.42
NOS1 P29475 1/20 0.42
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
IDO1 P14902 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
(Phenylamino)Acetonitrile SCHEMBL197012 0.84 ALDH1A1 (0.48) ALDH1A1MAPTTSHRHSD17B10SMN1; SMN2
(Phenylamino)Acetonitrile SCHEMBL26699804 0.82 ALDH1A1 (0.46) ALDH1A1MAPTTSHRHSD17B10SMN1; SMN2
(Phenylamino)Acetonitrile SCHEMBL7717385 0.82 MAPT (0.46) ALDH1A1MAPTTSHRHSD17B10SMN1; SMN2
SCHEMBL13192849 0.78 PGR (0.50) ALDH1A1MAPTLMNAMAPK1KDM4E
SCHEMBL11115631 0.77 ALDH1A1 (0.59) ALDH1A1MAPTLMNAKCNA5TSHR
SCHEMBL9172643 0.77 LOXL2 (0.48) ALDH1A1MAPTLMNATSHRMAPK1
SCHEMBL5885533 0.75 LMNA (0.48) ALDH1A1MAPTLMNAKCNA5HSD17B10
SCHEMBL28868850 0.75 EGFR (0.40) ALDH1A1MAPTLMNAHTTADORA2A
SCHEMBL8349873 0.75 L3MBTL1 (0.58) ALDH1A1MAPTLMNAKCNA5HSD17B10
SCHEMBL3671419 0.74 GABRG2 (0.50) ALDH1A1MAPTLMNAKCNA5HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4556508-A CYANIC GROUP CONTAINING MATERIAL; COPPER SULFIDE AND AUXILIARY METAL SULFIDE ADSORBED THERON NIHON SANMO DYEING CO., LTD. (JP) 1985-12-03 US claimed