SCHEMBL267396

SCHEMBL267396

O=C(Nc1ccc(F)c([Ti](C2=CC=CC2)(C2=CC=CC2)c2c(F)ccc(NC(=O)c3ccc(Cl)cc3)c2F)c1F)c1ccc(Cl)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 6/20 0.43
MEN1 O00255 4/20 0.43
RAB9A P51151 7/20 0.43
NPC1 O15118 5/20 0.43
CYP1A2 P05177 1/20 0.41
CYP2D6 P10635 1/20 0.41
CYP2C19 P33261 1/20 0.41
TP53 P04637 2/20 0.40
MDM4 O15151 1/20 0.40
MDM2 Q00987 1/20 0.40
KCNMA1 Q12791 1/20 0.38
POLB P06746 1/20 0.38
RXFP1 Q9HBX9 1/20 0.38
HDAC1 Q13547 2/20 0.38
LMNA P02545 1/20 0.37
KCNJ11 Q14654 1/20 0.37
KDM4E B2RXH2 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
GAA P10253 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL599353 0.91 POLB (0.45) KMT2AMEN1RAB9ANPC1KCNMA1
SCHEMBL482491 0.90 RAB9A (0.44) KMT2AMEN1RAB9ANPC1CYP1A2
SCHEMBL483372 0.86 RAB9A (0.42) KMT2AMEN1RAB9ANPC1CYP1A2
SCHEMBL268803 0.84 HPGD (0.44) KMT2AMEN1RAB9ANPC1CYP1A2
SCHEMBL483069 0.83 HDAC1 (0.39) RAB9ANPC1POLBRXFP1HDAC1
SCHEMBL483079 0.80 HTT (0.47) NPC1TP53KDM4E
SCHEMBL483118 0.80 KDM4E (0.35) RAB9ANPC1CYP1A2POLBKCNJ11
SCHEMBL483279 0.80 ALPL (0.38) KMT2AMEN1TP53POLBLMNA
SCHEMBL269422 0.80 PDK1 (0.34) KMT2AMEN1NPC1KCNJ11
SCHEMBL483181 0.80 NPC1 (0.40) KMT2AMEN1NPC1CYP1A2CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 96 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3431544-B1 COMPOSITION FOR PREPARING A FOAM, FOAM, AND SHOE EMPLOYING THE SAME TSRC CORP (TW) 2025-02-26 EP disclosed
EP-3182204-B1 PLANOGRAPHIC PRINTING PLATE PRECURSOR USING A POLYMERIZABLE COMPOSITION FUJIFILM CORP (JP) 2021-10-20 EP disclosed
US-10780679-B2 Laminate, method for manufacturing laminate, semiconductor device, and method for manufacturing the semiconductor device FUJIFILM CORPORATION (JP) 2020-09-22 US disclosed
EP-3431544-A1 COMPOSITION FOR PREPARING A FOAM, FOAM, AND SHOE EMPLOYING THE SAME TSRC Corporation (TW) 2019-01-23 EP disclosed
US-20180222164-A1 LAMINATE, METHOD FOR MANUFACTURING LAMINATE, SEMICONDUCTOR DEVICE, AND METHOD FOR MANUFACTURING THE SEMICONDUCTOR DEVICE FUJIFILM CORPORATION (JP) 2018-08-09 US disclosed
EP-3182204-A1 PLANOGRAPHIC PRINTING PLATE PRECURSOR USING A POLYMERIZABLE COMPOSITION FUJIFILM Corporation (JP) 2017-06-21 EP disclosed
EP-2109000-B1 Polymer having polymerizable group, polymerizable composition, planographic printing plate precursor, and planographic printing method using the same FUJIFILM CORP (JP) 2017-02-22 EP disclosed
EP-2105795-B1 Resin composition for laser engraving, image forming material, relief printing plate precursor for laser engraving, relief printing plate, and method of manufacturing relief printing plate FUJIFILM CORP (JP) 2016-12-28 EP disclosed
EP-1887423-B1 Laser-decomposable resin composition and pattern-forming material using the same FUJIFILM CORP (JP) 2016-01-27 EP disclosed
EP-2085220-B1 Resin composition for laser engraving, relief printing plate precursor for laser engraving, relief printing plate and method of producing the same FUJIFILM CORP (JP) 2015-05-20 EP disclosed
US-6727044-B1 LASER SCANNING LITHOGRAPHIC PRINTING ORIGINAL PLATE WHICH CAN PROVIDE A PRINTING PLATE HAVING A SUFFICIENTLY LONG PRESS LIFE EVEN BY HIGH-SPEED SCAN EXPOSURE AND CAUSES LITTLE FLUCTUATION IN THE PRINTING PERFORMANCE OF THE PRINTING PLATE FUJI PHOTO FILM CO., LTD. (JP) 2004-04-27 US disclosed
US-20040043325-A1 Polymerizable composition and negative-working planographic printing plate precursor using the same FUJI PHOTO FILM CO., LTD. 2004-03-04 US disclosed
EP-1391784-A2 Polymerizable composition and negative-working planographic printing plate precursor using the same FUJI PHOTO FILM CO., LTD. (JP) 2004-02-25 EP disclosed
US-20030190554-A1 Photopolymerization; development using alkalinity developer FUJIFILM CORPORATION (JP) 2003-10-09 US disclosed
US-20030091933-A1 Photosensitive composition and negative working lithographic printing plate FUJIFILM CORPORATION (JP) 2003-05-15 US disclosed
US-20030084806-A1 FINE PARTICLES CONTAINING A RADICAL POLYMERIZABLE ENCAPSULATED BY MICROCAPSULES FUJIFILM CORPORATION (JP) 2003-05-08 US disclosed
EP-1288720-A1 Plate-making method of printing plate FUJI PHOTO FILM CO., LTD. (JP) 2003-03-05 EP disclosed
EP-1249731-A2 Photosensitive composition and negative working lithographic printing plate FUJI PHOTO FILM CO., LTD. (JP) 2002-10-16 EP disclosed
EP-1238801-A2 Lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2002-09-11 EP disclosed
EP-0949540-A1 Method for producing lithographic printing plate suitable for laser scan exposure, and photopolymerizable composition FUJI PHOTO FILM CO., LTD (JP) 1999-10-13 EP disclosed