SCHEMBL268803

SCHEMBL268803

O=C(Nc1ccc(F)c([Ti](C2=CC=CC2)(C2=CC=CC2)c2c(F)ccc(NC(=O)c3ccccc3Cl)c2F)c1F)c1ccccc1Cl

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 2/20 0.44
CYP1A2 P05177 2/20 0.44
CYP2C19 P33261 2/20 0.44
RAB9A P51151 3/20 0.44
GRM4 Q14833 1/20 0.43
KDM4E B2RXH2 2/20 0.43
ALDH1A1 P00352 4/20 0.43
KMT2A Q03164 2/20 0.43
NPC1 O15118 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
LMNA P02545 1/20 0.41
MAPT P10636 1/20 0.41
TP53 P04637 2/20 0.40
EPHB3 P54753 1/20 0.40
MEN1 O00255 1/20 0.40
POLB P06746 1/20 0.39
CYP3A4 P08684 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
KCNMA1 Q12791 1/20 0.37
SLC16A3 O15427 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL483289 0.87 RECQL (0.39) HPGDCYP1A2CYP2C19RAB9AALDH1A1
SCHEMBL482491 0.84 RAB9A (0.44) HPGDCYP1A2CYP2C19RAB9AALDH1A1
SCHEMBL267396 0.84 KMT2A (0.43) CYP1A2CYP2C19RAB9AKDM4EKMT2A
SCHEMBL483000 0.83 ALDH1A1 (0.36) HPGDRAB9AKDM4EALDH1A1KMT2A
SCHEMBL482975 0.83 TP53 (0.34) HPGDRAB9AALDH1A1KMT2ANPC1
SCHEMBL269338 0.83 HDAC3 (0.38) HPGDRAB9AALDH1A1KMT2ANPC1
SCHEMBL483069 0.83 HDAC1 (0.39) RAB9AKDM4EALDH1A1NPC1SMN1; SMN2
SCHEMBL483287 0.82 L3MBTL1 (0.35) HPGDRAB9AKDM4EALDH1A1KMT2A
SCHEMBL483355 0.81 ALDH1A1 (0.39) RAB9AKDM4EALDH1A1NPC1SMN1; SMN2
SCHEMBL5198749 0.80 SLC16A3 (0.37) CYP1A2CYP2C19RAB9AKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 89 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3431544-B1 COMPOSITION FOR PREPARING A FOAM, FOAM, AND SHOE EMPLOYING THE SAME TSRC CORP (TW) 2025-02-26 EP disclosed
EP-3182204-B1 PLANOGRAPHIC PRINTING PLATE PRECURSOR USING A POLYMERIZABLE COMPOSITION FUJIFILM CORP (JP) 2021-10-20 EP disclosed
US-10780679-B2 Laminate, method for manufacturing laminate, semiconductor device, and method for manufacturing the semiconductor device FUJIFILM CORPORATION (JP) 2020-09-22 US disclosed
EP-3431544-A1 COMPOSITION FOR PREPARING A FOAM, FOAM, AND SHOE EMPLOYING THE SAME TSRC Corporation (TW) 2019-01-23 EP disclosed
US-20180222164-A1 LAMINATE, METHOD FOR MANUFACTURING LAMINATE, SEMICONDUCTOR DEVICE, AND METHOD FOR MANUFACTURING THE SEMICONDUCTOR DEVICE FUJIFILM CORPORATION (JP) 2018-08-09 US disclosed
EP-3182204-A1 PLANOGRAPHIC PRINTING PLATE PRECURSOR USING A POLYMERIZABLE COMPOSITION FUJIFILM Corporation (JP) 2017-06-21 EP disclosed
EP-2109000-B1 Polymer having polymerizable group, polymerizable composition, planographic printing plate precursor, and planographic printing method using the same FUJIFILM CORP (JP) 2017-02-22 EP disclosed
EP-2105795-B1 Resin composition for laser engraving, image forming material, relief printing plate precursor for laser engraving, relief printing plate, and method of manufacturing relief printing plate FUJIFILM CORP (JP) 2016-12-28 EP disclosed
EP-1887423-B1 Laser-decomposable resin composition and pattern-forming material using the same FUJIFILM CORP (JP) 2016-01-27 EP disclosed
EP-2085220-B1 Resin composition for laser engraving, relief printing plate precursor for laser engraving, relief printing plate and method of producing the same FUJIFILM CORP (JP) 2015-05-20 EP disclosed
US-6858373-B2 Photosensitive composition and negative working lithographic printing plate FUJI PHOTO FILM CO., LTD. (JP) 2005-02-22 US disclosed
US-20050031986-A1 Radical polymerizable composition and lithographic printing plate precursor using the same FUJI PHOTO FILM CO., LTD. 2005-02-10 US disclosed
EP-1449651-A2 Polymerizable composition and lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2004-08-25 EP disclosed
US-6727044-B1 LASER SCANNING LITHOGRAPHIC PRINTING ORIGINAL PLATE WHICH CAN PROVIDE A PRINTING PLATE HAVING A SUFFICIENTLY LONG PRESS LIFE EVEN BY HIGH-SPEED SCAN EXPOSURE AND CAUSES LITTLE FLUCTUATION IN THE PRINTING PERFORMANCE OF THE PRINTING PLATE FUJI PHOTO FILM CO., LTD. (JP) 2004-04-27 US disclosed
US-20030190554-A1 Photopolymerization; development using alkalinity developer FUJIFILM CORPORATION (JP) 2003-10-09 US disclosed
US-20030091933-A1 Photosensitive composition and negative working lithographic printing plate FUJIFILM CORPORATION (JP) 2003-05-15 US disclosed
EP-1288720-A1 Plate-making method of printing plate FUJI PHOTO FILM CO., LTD. (JP) 2003-03-05 EP disclosed
EP-1249731-A2 Photosensitive composition and negative working lithographic printing plate FUJI PHOTO FILM CO., LTD. (JP) 2002-10-16 EP disclosed
EP-1238801-A2 Lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2002-09-11 EP disclosed
EP-0949540-A1 Method for producing lithographic printing plate suitable for laser scan exposure, and photopolymerizable composition FUJI PHOTO FILM CO., LTD (JP) 1999-10-13 EP disclosed