Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 6/20 | 0.45 |
| ▸ | DRD4 | P21917 | 4/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 3/20 | 0.43 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.41 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.41 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.41 |
| ▸ | GRM2 | Q14416 | 4/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | CCR2 | P41597 | 2/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26817280 | 0.88 | MCHR1 (0.40) | DRD4SIGMAR1GRM2MCHR1DRD3 | |
| SCHEMBL26817271 | 0.77 | HRH3 (0.40) | SIGMAR1 | |
| SCHEMBL26817286 | 0.75 | HTR1A (0.37) | DRD2SIGMAR1 | |
| SCHEMBL26817285 | 0.74 | GRM2 (0.38) | GRM2MCHR1USP2KCNH2 | |
| SCHEMBL26817278 | 0.73 | HTR1A (0.36) | SIGMAR1KCNH2 | |
| SCHEMBL22016170 | 0.72 | KIF11 (0.42) | MEN1KMT2ATLR9 | |
| SCHEMBL22017134 | 0.71 | ATM (0.38) | MEN1KMT2A | |
| SCHEMBL26815145 | 0.68 | AR (0.39) | USP2 | |
| SCHEMBL4331832 | 0.66 | LMNA (0.50) | DRD2DRD4MEN1KMT2AGRM2 | |
| SCHEMBL1002852 | 0.65 | MEN1 (0.81) | DRD2DRD4SIGMAR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023220741-A1 | ALPHA 4 BETA 7 INTEGRIN MODULATORS AND USES THEREOF | DICE MOLECULES SV, INC. (US) | 2023-11-16 | — | — | WO | disclosed |