Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.40 |
| ▸ | HTR1A | P08908 | 2/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.38 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26817286 | 0.91 | HTR1A (0.37) | HRH3HTR1ASIGMAR1 | |
| SCHEMBL26817278 | 0.87 | HTR1A (0.36) | HTR1ASIGMAR1 | |
| SCHEMBL26817280 | 0.82 | MCHR1 (0.40) | HRH3SIGMAR1ACHE | |
| SCHEMBL26807679 | 0.77 | DRD2 (0.45) | SIGMAR1 | |
| SCHEMBL22017134 | 0.76 | ATM (0.38) | — | |
| SCHEMBL26815145 | 0.73 | AR (0.39) | — | |
| SCHEMBL26817285 | 0.73 | GRM2 (0.38) | HRH3L3MBTL1 | |
| SCHEMBL22016170 | 0.72 | KIF11 (0.42) | L3MBTL1 | |
| SCHEMBL22017359 | 0.68 | KDM4E (0.36) | — | |
| SCHEMBL26817066 | 0.66 | ALDH1A1 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023220741-A1 | ALPHA 4 BETA 7 INTEGRIN MODULATORS AND USES THEREOF | DICE MOLECULES SV, INC. (US) | 2023-11-16 | — | — | WO | disclosed |