Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB3 | Q13509 | 2/20 | 0.38 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.38 |
| ▸ | TUBB | P07437 | 1/20 | 0.38 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.38 |
| ▸ | STAT3 | P40763 | 1/20 | 0.38 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.38 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.38 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.38 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.38 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.38 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.38 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.38 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.38 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.38 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.38 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13237058 | 0.84 | TUBB3 (0.49) | TUBB3TUBB4ATUBBTUBA3CSTAT3 | |
| SCHEMBL31493151 | 0.83 | KIF11 (0.39) | KMT2A | |
| SCHEMBL10160687 | 0.80 | TUBB4A (0.46) | TUBB3TUBB4ATUBBTUBA3CSTAT3 | |
| SCHEMBL25954101 | 0.80 | ALDH1A1 (0.41) | RAB9AKMT2ANPC1TDP1 | |
| SCHEMBL12047794 | 0.79 | EGFR (0.49) | TUBB3TUBB4ATUBBTUBA3CSTAT3 | |
| SCHEMBL14018310 | 0.79 | TUBB4A (0.45) | TUBB3TUBB4ATUBBTUBA3CSTAT3 | |
| SCHEMBL16344206 | 0.77 | TUBB4A (0.48) | TUBB3TUBB4ATUBBTUBA3CSTAT3 | |
| SCHEMBL12333047 | 0.77 | TUBB4A (0.48) | TUBB3TUBB4ATUBBTUBA3CSTAT3 | |
| SCHEMBL17690847 | 0.77 | TUBB4A (0.48) | TUBB3TUBB4ATUBBTUBA3CSTAT3 | |
| SCHEMBL1011203 | 0.77 | KIF11 (0.45) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230359068-A1 | OPTICAL ARTICLE, SPECTACLES, AND PHOTOCHROMIC COMPOUND | HOYA LENS THAILAND LTD. (TH) | 2023-11-09 | — | — | US | disclosed |
| US-20230359068-A1 | OPTICAL ARTICLE, SPECTACLES, AND PHOTOCHROMIC COMPOUND | HOYA LENS THAILAND LTD. (TH) | 2023-11-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230359068-A1 | OPTICAL ARTICLE, SPECTACLES, AND PHOTOCHROMIC COMPOUND | GRK1, TCOF1, ARPC1B | TUBB3 472/4885TUBB4A 1254/4885TUBB 901/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.