SCHEMBL2912954

SCHEMBL2912954

Cc1nc(-c2ccccc2)cnc1-c1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 4/20 0.53
RAB9A P51151 3/20 0.53
NPC1 O15118 1/20 0.53
PDGFRB P09619 1/20 0.53
KDR P35968 1/20 0.53
FLT3 P36888 1/20 0.53
ALDH1A1 P00352 4/20 0.47
KDM4E B2RXH2 3/20 0.47
MEN1 O00255 3/20 0.47
KMT2A Q03164 3/20 0.47
MAPT P10636 2/20 0.47
POLB P06746 1/20 0.47
PKM P14618 1/20 0.47
CKS1B P61024 1/20 0.46
SKP1 P63208 1/20 0.46
SKP2 Q13309 1/20 0.46
GLA P06280 1/20 0.45
GAA P10253 1/20 0.45
HDAC6 Q9UBN7 1/20 0.45
HPGD P15428 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12539180 0.96 SMN1; SMN2 (0.50) SMN1; SMN2RAB9ANPC1PDGFRBKDR
SCHEMBL10205870 0.84 RAB9A (0.53) SMN1; SMN2RAB9ANPC1PDGFRBKDR
SCHEMBL15256055 0.84 RAB9A (0.50) SMN1; SMN2RAB9ANPC1PDGFRBKDR
SCHEMBL469153 0.84 HCRTR1 (0.47) SMN1; SMN2RAB9ANPC1PDGFRBKDR
SCHEMBL3335530 0.82 JAK3 (0.56) SMN1; SMN2RAB9AALDH1A1KDM4EMEN1
SCHEMBL29476061 0.82 JAK3 (0.56) SMN1; SMN2RAB9AALDH1A1KDM4EMEN1
SCHEMBL16622240 0.81 RAB9A (0.47) SMN1; SMN2RAB9ANPC1PDGFRBKDR
SCHEMBL87574 0.81 CKS1B (0.55) SMN1; SMN2RAB9ANPC1PDGFRBKDR
SCHEMBL28313697 0.80 JAK3 (0.54) SMN1; SMN2RAB9AALDH1A1KDM4EMEN1
SCHEMBL29403615 0.80 JAK3 (0.54) SMN1; SMN2RAB9AALDH1A1KDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11800796-B2 Luminescent material for delayed fluorescence and organic electroluminescent device comprising the same ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. 2023-10-24 US disclosed
US-10454042-B2 Organic electroluminescence device UDC IRELAND LIMITED (IE) 2019-10-22 US disclosed
US-10103341-B2 Organometallic complex and light emitting element, light emitting device, and electronic device using the organometallic complex SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2018-10-16 US disclosed
US-20180190912-A1 LUMINESCENT MATERIAL FOR DELAYED FLUORESCENCE AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD (KR) 2018-07-05 US disclosed
CN-105061514-B Organometallic complex and light-emitting component, light-emitting device and electronic device 株式会社半导体能源研究所 2018-05-08 CN disclosed
US-20160079545-A1 Organic Electroluminescence Device UDC Ireland (IE) 2016-03-17 US disclosed
US-9287515-B2 Compositions comprising organic and organometallic compounds, and their applications in organic electroluminescence, light emission, display, and illumination devices UDC Ireland (IE) 2016-03-15 US disclosed
CN-105061514-A Organometallic complex and light emitting element, light emitting device, and electronic device using the organometallic complex SEMICONDUCTOR ENERGY LAB 2015-11-18 CN disclosed
US-20150214484-A1 Organometallic Complex and Light Emitting Element, Light Emitting Device, and Electronic Device Using the Organometallic Complex SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-07-30 US disclosed
US-20150214484-A1 Organometallic Complex and Light Emitting Element, Light Emitting Device, and Electronic Device Using the Organometallic Complex SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-07-30 US disclosed
EP-2254173-A1 Organometallic complex and light emitting element, light emitting device, and electronic device using the organometallic complex Semiconductor Energy Laboratory Co, Ltd. (JP) 2010-11-24 EP disclosed
EP-1873163-B1 Organometallic complex and light emitting element, light emitting device, and electronic device using the organometallic complex SEMICONDUCTOR ENERGY LAB (JP) 2010-08-25 EP disclosed
EP-1873163-B1 Organometallic complex and light emitting element, light emitting device, and electronic device using the organometallic complex SEMICONDUCTOR ENERGY LAB (JP) 2010-08-25 EP disclosed
US-20090302742-A1 Compound for Use in Organic Electroluminescent Device and Organic Electroluminescent Device NIPPON STEEL CHEMICAL CO., LTD. (JP) 2009-12-10 US disclosed
CN-101270133-A Organometallic complex, light-emitting element, light-emitting device, and electronic device SEMICONDUCTOR ENERGY LAB (JP) 2008-09-24 CN disclosed
EP-1873163-A1 Organometallic complex and light emitting element, light emitting device, and electronic device using the organometallic complex SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2008-01-02 EP disclosed
EP-1873163-A1 Organometallic complex and light emitting element, light emitting device, and electronic device using the organometallic complex SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2008-01-02 EP disclosed
US-20070244320-A1 Organometallic complex and light emitting element, light emitting device, and electronic device using the organometallic complex SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2007-10-18 US disclosed
US-20070244320-A1 Organometallic complex and light emitting element, light emitting device, and electronic device using the organometallic complex SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2007-10-18 US disclosed
US-20070244320-A1 Organometallic complex and light emitting element, light emitting device, and electronic device using the organometallic complex SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2007-10-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11800796-B2 Luminescent material for delayed fluorescence and organic electroluminescent device comprising the same TRPC6, TRPC5, ZNF436-AS1 SMN1; SMN2 1026/4885RAB9A 1646/4885NPC1 3816/4885
US-10103341-B2 Organometallic complex and light emitting element, light emitting device, and electronic device using the organometallic complex CRY1, AP1M1, AP2M1 SMN1; SMN2 4230/4885RAB9A 1961/4885NPC1 2426/4885
US-20090302742-A1 Compound for Use in Organic Electroluminescent Device and Organic Electroluminescent Device LAGE3, ICMT, PPOX SMN1; SMN2 4361/4885RAB9A 2408/4885NPC1 4722/4885
US-20180190912-A1 LUMINESCENT MATERIAL FOR DELAYED FLUORESCENCE AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME TRPC6, TRPC5, ZNF436-AS1 SMN1; SMN2 1026/4885RAB9A 1646/4885NPC1 3816/4885
US-10454042-B2 Organic electroluminescence device EML4, ELOC, ORC3 SMN1; SMN2 3871/4885RAB9A 3982/4885NPC1 4077/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.