Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | ACP3 | P15309 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.38 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TDO2 | P48775 | 2/20 | 0.37 |
| ▸ | IDO2 | Q6ZQW0 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.36 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22300264 | 0.79 | GABRA1 (0.42) | APPIDO1ALDH1A1MAPTLMNA | |
| SCHEMBL17765434 | 0.78 | ALDH1A1 (0.46) | APPIDO1ALDH1A1MAPTLMNA | |
| SCHEMBL2686082 | 0.78 | IDO1 (0.44) | APPACP3IDO1ALDH1A1LMNA | |
| SCHEMBL9670146 | 0.78 | CES2 (0.40) | APPIDO1ALDH1A1MAPTLMNA | |
| SCHEMBL9667703 | 0.78 | APP (0.39) | APPIDO1ALDH1A1MAPTLMNA | |
| SCHEMBL9578317 | 0.77 | MAPT (0.58) | APPIDO1ALDH1A1MAPTLMNA | |
| SCHEMBL2803296 | 0.75 | ALDH1A1 (0.44) | APPACP3IDO1ALDH1A1LMNA | |
| SCHEMBL9578277 | 0.75 | ALDH1A1 (0.38) | APPIDO1ALDH1A1MAPTLMNA | |
| SCHEMBL29288280 | 0.75 | GRM5 (0.44) | IDO1CYP19A1TDO2HTTL3MBTL1 | |
| SCHEMBL7202374 | 0.75 | ALDH1A1 (0.39) | ALDH1A1ADRB2ADRB1AOC3MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113461501-A | Green method for high-selectivity synthesis of chalcone compounds | 温州大学 | 2021-10-01 | — | — | CN | disclosed |
| US-8168835-B2 | Method for preparing propargylic alcohol catalyzed by 2-morpholinoisobornane-10-thiol | NATIONAL TSING HUA UNIVERSITY (TW) | 2012-05-01 | — | — | US | disclosed |
| US-20110295042-A1 | METHOD FOR PREPARING PROPARGYLIC ALCOHOL CATALYZED BY 2-MORPHOLINOISOBORNANE-10-THIOL | NATIONAL TSING HUA UNIVERSITY (TW) | 2011-12-01 | — | — | US | disclosed |
| EP-0256745-B1 | CRYSTALLINE COMPLEX COMPOUNDS OF PROPARGYL ALCOHOLS AND TERTIARY DIAMINES, AND PROCESS OF SEPARATION AND PURIFICATION OF PROPARGYL ALCOHOLS USING THE SAME | UBE INDUSTRIES, LTD. (JP) | 1992-05-13 | — | — | EP | disclosed |
| EP-0256745-A2 | Crystalline complex compounds of propargyl alcohols and tertiary diamines, and process of separation and purification of propargyl alcohols using the same | UBE INDUSTRIES, LTD. (JP) | 1988-02-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110295042-A1 | METHOD FOR PREPARING PROPARGYLIC ALCOHOL CATALYZED BY 2-MORPHOLINOISOBORNANE-10-THIOL | GRHPR, ADH1C, ADH5 | APP 3945/4885ACP3 4748/4885IDO1 3612/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.