SCHEMBL2687569

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2688404	0.86	MET (0.43)	METALDH1A1HPGDMEN1KMT2A
	SCHEMBL2688587	0.85	CYP11B2 (0.42)	METALDH1A1HPGDMEN1KMT2A
	SCHEMBL2686059	0.83	OPRM1 (0.43)	METALDH1A1HPGDHSPD1PTPN5
	SCHEMBL2688684	0.83	MET (0.44)	METALDH1A1HPGDMEN1KMT2A
	SCHEMBL15693825	0.83	BCAT2 (0.34)	ALDH1A1HPGDKDM4ENPC1RAB9A
	SCHEMBL10219917	0.83	MET (0.43)	METALDH1A1HPGDHSPD1PTPN5
	SCHEMBL2687495	0.82	ALOX5 (0.46)	METALDH1A1HPGDMEN1KMT2A
	SCHEMBL2686061	0.82	NPC1 (0.47)	METALDH1A1HPGDCYP1A2CYP2C19
	SCHEMBL2686461	0.82	MET (0.41)	METALDH1A1HPGDMEN1KMT2A
	SCHEMBL2687450	0.82	MET (0.42)	METALDH1A1HPGDKDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.