Water

Water

SCHEMBL270067

O.O.O.O.O.O.[Cl-].[Cl-].[Cl-].[Gd+3]

nearest known ligand 0.00

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO

The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL4774062 1.00
Water SCHEMBL2289874 1.00
Water SCHEMBL28208506 1.00
Hydrochloric Acid SCHEMBL4823672 0.82
Hydrochloric Acid SCHEMBL248474 0.82
Water SCHEMBL23461833 0.67
Water SCHEMBL23631871 0.67
Water SCHEMBL20562889 0.67
Water SCHEMBL25334174 0.67
Water SCHEMBL21379772 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 839 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120022874-B Preparation method of imprinting functional straw adsorbent 山东理工大学 2025-06-24 CN claimed
CN-119799318-B Au (gold) alloy2S-up-conversion luminescence nanocomposite and preparation method thereof 内蒙古科学技术研究院 2025-06-03 CN claimed
CN-114813688-B Method for detecting acrylamide content based on up-conversion nano biosensing system 江苏大学 2025-06-03 CN claimed
CN-120025353-A Application of magneto-optical dual-function material based on beta-diketone rare earth gadolinium complex in fluorescence imaging 宁夏医科大学 2025-05-23 CN claimed
CN-120022874-A Preparation method of imprinting functional straw adsorbent 山东理工大学 2025-05-23 CN claimed
CN-119799318-A Au (gold) alloy2S-up-conversion luminescence nanocomposite and preparation method thereof 内蒙古科学技术研究院 2025-04-11 CN claimed
CN-115060696-B Preparation method of dual-signal sensor and application of dual-signal sensor in nitrite detection 江苏大学 2025-04-08 CN claimed
CN-119752101-A Preparation method and material of MOFs modified foam metal/functional resin composite material for neutron/gamma ray shielding 南京航空航天大学 2025-04-04 CN claimed
CN-119684384-A Nitroreductase response fluorescence and magnetic resonance bimodal probe NO designed based on gemcitabine prodrug2-Cy-Gxtb-Gd-Biotin and synthetic method and application thereof 中国科学院精密测量科学与技术创新研究院 2025-03-25 CN claimed
CN-119601693-A Rare earth doped Pt-based high-entropy intermetallic compound, preparation and application 吉林大学 2025-03-11 CN claimed
US-20080249298-A1 USE OF HEPARINOID DERIVATIVES FOR THE TREATMENT AND DIAGNOSIS OF DISORDERS WHICH CAN BE TREATED WITH HEPARINOIDS SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) 2008-10-09 US claimed
WO-2007142804-A2 PREPARATION OF COMPLEXING AGENTS AND METAL ION COMPLEXES IN AQUEOUS MEDIA MALLINCKRODT INC. (US) 2007-12-13 WO claimed
WO-2007100541-A2 METHOD OF TREATING PERIODONTITIS AND OF REDUCING DENTINAL SENSITIVITY RESEARCH FOUNDATION OF THE STATE UNIVERSITY OF NEW YORK (US) 2007-09-07 WO claimed
US-20070196288-A1 Method of treating periodontitis and of reducing dentinal sensitivity RESEARCH FOUNDATION OF THE STATE UNIVERSITY OF NEW YORK 2007-08-23 US claimed
EP-1423436-B1 USE OF HEPARINOID DERIVATIVES FOR TREATING AND DIAGNOSING DISEASES THAT CAN BE TREATED BY HEPARINOIDS SANOFI AVENTIS DEUTSCHLAND (DE) 2006-04-12 EP claimed
US-20030109491-A1 Use of heparinoid derivatives for the treatment and diagnosis of disorders which can be treated with heparinoids SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) 2003-06-12 US claimed
US-6534040-B2 Chlorin and bacteriochlorin-based aminophenyl DTPA and N2S2 conjugates for MR contrast media and radiopharmaceuticals HEALTH RESEARCH, INC. 2003-03-18 US claimed
EP-0754690-B1 Gadolinium-DTPA complex containing carborane unit, intermediates thereof and method of synthesizing them UNIV TOHOKU (JP) 2002-02-13 EP claimed
US-5714591-A DIETHYLENETRIAMINEPENTAACETIC ACID COMPLEX; USED AS CONTRASTING AGENT FOR MRI'S AND NEUTRON CAPTURE THERAPY IN THE RADIOTHERAPY OF CANCERS AND TUMORS PRESIDENT OF TOHOKU UNIVERSITY (JP) 1998-02-03 US claimed
EP-0754690-A1 Gadolinium-DTPA complex containing carborane unit, intermediates thereof and method of synthesizing them President of TOHOKU UNIVERSITY (JP) 1997-01-22 EP claimed