Water

Water

SCHEMBL4774062

O.[Cl-].[Cl-].[Cl-].[Gd+3]

nearest known ligand 0.00

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO

The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL2289874 1.00
Water SCHEMBL270067 1.00
Water SCHEMBL28208506 1.00
Hydrochloric Acid SCHEMBL4823672 0.82
Hydrochloric Acid SCHEMBL248474 0.82
Water SCHEMBL23461833 0.67
Water SCHEMBL23631871 0.67
Water SCHEMBL20562889 0.67
Water SCHEMBL25334174 0.67
Water SCHEMBL21379772 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 82 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240277874-A1 FLUORESCENCE-MAGNETIC RESONANCE DUAL-MODALITY CONTRAST AGENT, PREPARATION METHOD THEREFOR AND USE THEREOF HAINAN POLY PHARMACEUTICAL CO., LTD. (CN) 2024-08-22 US claimed
EP-4342499-A1 FLUORESCENCE-MAGNETIC RESONANCE BIMODAL CONTRAST AGENT, PREPARATION METHOD THEREFOR AND USE THEREOF Hainan Poly Pharmaceutical Co, .Ltd. (CN) 2024-03-27 EP claimed
CN-115467091-B Bismuth oxide/gadolinium oxide nanofiber membrane alternately-stacked composite material and preparation method thereof 东华大学 2023-07-04 CN claimed
WO-2022242437-A1 FLUORESCENCE-MAGNETIC RESONANCE BIMODAL CONTRAST AGENT, PREPARATION METHOD THEREFOR AND USE THEREOF 海南普利制药股份有限公司 2022-11-24 WO claimed
CN-115364245-A Fluorescence-magnetic resonance bimodal contrast agent and preparation method and application thereof 海南普利制药股份有限公司 2022-11-22 CN claimed
CN-112320833-B High temperature resistant SiO 2 -Gd 2 O 3 Composite aerogel and preparation method thereof 湖南荣岚智能科技有限公司 2022-08-02 CN claimed
US-10307735-B2 Gd-containing, anti-coking solid acid catalysts and preparation method and use thereof KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2019-06-04 US claimed
CN-109385271-A A kind of fluorescent material and preparation method thereof based on amino acid eutectic solvent 河北科技大学 2019-02-26 CN claimed
CN-107998390-A A kind of photo-thermal diagnosis Integral rice grain of difunctional imaging guiding and preparation method thereof 湖北大学 2018-05-08 CN claimed
US-20180065110-A1 GD-CONTAINING, ANTI-COKING SOLID ACID CATALYSTS AND PREPARATION METHOD AND USE THEREOF KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2018-03-08 US claimed
US-9796923-B2 Color tunable multifunctional nanophosphor, synthesis method thereof, and polymer composite including the nanophosphor KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2017-10-24 US claimed
CN-104599725-B A kind of soluble gadolinium base neutron poison medicament and preparation method thereof 中国核电工程有限公司 2017-07-28 CN claimed
CN-104599725-A Soluble gadolinium-based neutron poison potion and preparation method thereof CHINA NUCLEAR POWER ENG CO LTD 2015-05-06 CN claimed
US-20140308213-A1 COLOR TUNABLE MULTIFUNCTIONAL NANOPHOSPHOR, SYNTHESIS METHOD THEREOF, AND POLYMER COMPOSITE INCLUDING THE NANOPHOSPHOR KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2014-10-16 US claimed
US-12577463-B2 Multi-color tunable upconversion nanophosphor KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2026-03-17 US disclosed
EP-4206300-B1 VERSATILE COLOR-TUNABLE UPCONVERSION NANOPHOSPHOR KOREA INST SCI & TECH (KR) 2026-03-11 EP disclosed
CN-119553126-A Hard alloy for deep drilling of complex rock stratum and preparation method thereof 成都岷江精密刀具有限公司 2025-03-04 CN disclosed
WO-2004031221-A9 TUMOR TARGETING AGENTS AND USES THEREOF KARYON OY (FI) 2004-07-08 WO disclosed
WO-2004031218-A1 TUMOR TARGETING AGENTS AND USES THEREOF KARYON OY (FI) 2004-04-15 WO disclosed
WO-2004031221-A1 TUMOR TARGETING AGENTS AND USES THEREOF KARYON OY (FI) 2004-04-15 WO disclosed