Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IMPDH2 | P12268 | 1/20 | 0.43 |
| ▸ | ACACB | O00763 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 7/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | MEN1 | O00255 | 6/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.42 |
| ▸ | NPC1 | O15118 | 6/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27045825 | 0.86 | IMPDH2 (0.40) | IMPDH2ACACBNAMPTAAK1RAB9A | |
| SCHEMBL23628809 | 0.80 | KMT2A (0.53) | RAB9AALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL27045997 | 0.78 | PTGS2 (0.50) | AAK1RAB9AALDH1A1MEN1KMT2A | |
| SCHEMBL27045508 | 0.77 | PTGS2 (0.54) | RAB9AALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL27045996 | 0.77 | PTGS2 (0.41) | IMPDH2ACACBAAK1RAB9AALDH1A1 | |
| SCHEMBL27045994 | 0.75 | PTGS2 (0.42) | AAK1RAB9AALDH1A1MEN1KMT2A | |
| SCHEMBL27045351 | 0.70 | HPGDS (0.35) | ACACBAAK1RAB9AALDH1A1NPC1 | |
| SCHEMBL23628862 | 0.69 | KMT2A (0.51) | RAB9AALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL27049956 | 0.68 | PTGS2 (0.41) | ALDH1A1MEN1KMT2AMAPTHSD17B10 | |
| SCHEMBL1745328 | 0.68 | MAPT (0.62) | RAB9AALDH1A1MEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3846793-B1 | EIF4E INHIBITORS AND USES THEREOF | PIC THERAPEUTICS INC (US) | 2024-01-24 | — | — | EP | disclosed |