SCHEMBL2709443

SCHEMBL2709443

Nc1ccc(C2(c3ccc(N)cc3)C3CC4CC(C3)CC2C4)cc1

nearest known ligand 0.55

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.55
LMNA P02545 2/20 0.55
PGR P06401 1/20 0.41
NSD2 O96028 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
HSD11B1 P28845 6/20 0.37
POLB P06746 1/20 0.36
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
MAPT P10636 1/20 0.35
CYP19A1 P11511 4/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2708160 0.89 ALDH1A1 (0.48) ALDH1A1LMNAPGRHSD11B1POLB
SCHEMBL26145358 0.83 ALDH1A1 (0.55) ALDH1A1LMNAPGRNSD2L3MBTL1
SCHEMBL23198946 0.78 MEN1 (0.40) ALDH1A1LMNAHSD11B1MEN1KMT2A
SCHEMBL22685825 0.78 CXCR3 (0.38) ALDH1A1LMNAHSD11B1MEN1KMT2A
SCHEMBL175542 0.78 HSD11B1 (0.41) ALDH1A1LMNAHSD11B1POLBMEN1
SCHEMBL1353430 0.77 HSD11B1 (0.52) HSD11B1MEN1KMT2A
SCHEMBL24173748 0.76 CYP3A4 (0.39) ALDH1A1LMNAHSD11B1
SCHEMBL23198930 0.76 CYP3A4 (0.39) ALDH1A1LMNAHSD11B1
SCHEMBL8766773 0.74 HSD11B1 (0.56) HSD11B1
SCHEMBL2710599 0.74 GAA (0.42) ALDH1A1LMNAL3MBTL1HSD11B1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11905381-B2 Polyimide microparticles XEROX CORPORATION (US) 2024-02-20 US claimed
CN-115322398-A Polyimide fine particles 施乐公司 2022-11-11 CN claimed
JP-7145116-A None JP disclosed
US-11920040-B2 Carborhodamine compounds and methods of preparation thereof ELITECHGROUP MDX LLC (US) 2024-03-05 US disclosed
US-11905381-B2 Polyimide microparticles XEROX CORPORATION (US) 2024-02-20 US disclosed
US-11785841-B2 Compound, display panel and display apparatus WUHAN TIANMA MICROELECTRONICS CO., LTD. (CN) 2023-10-10 US disclosed
US-11785841-B2 Compound, display panel and display apparatus WUHAN TIANMA MICROELECTRONICS CO., LTD. (CN) 2023-10-10 US disclosed
US-20230200218-A1 LIGHT-EMITTING DEVICE INCLUDING AMINE COMPOUND, ELECTRONIC APPARATUS INCLUDING THE LIGHT-EMITTING DEVICE, AND THE AMINE COMPOUND SAMSUNG DISPLAY CO., LTD. (KR) 2023-06-22 US disclosed
US-20230200218-A1 LIGHT-EMITTING DEVICE INCLUDING AMINE COMPOUND, ELECTRONIC APPARATUS INCLUDING THE LIGHT-EMITTING DEVICE, AND THE AMINE COMPOUND SAMSUNG DISPLAY CO., LTD. (KR) 2023-06-22 US disclosed
US-20230157157-A1 LIGHT-EMITTING DEVICE INCLUDING DIAMINE-BASED COMPOUND, ELECTRONIC APPARATUS INCLUDING THE LIGHT-EMITTING DEVICE, AND THE DIAMINE-BASED COMPOUND SAMSUNG DISPLAY CO LTD (KR) 2023-05-18 US disclosed
US-20230157157-A1 LIGHT-EMITTING DEVICE INCLUDING DIAMINE-BASED COMPOUND, ELECTRONIC APPARATUS INCLUDING THE LIGHT-EMITTING DEVICE, AND THE DIAMINE-BASED COMPOUND SAMSUNG DISPLAY CO LTD (KR) 2023-05-18 US disclosed
US-7365231-B2 Compound with antitumor activity and preparation method therefor NATIONAL TAIWAN UNIVERSITY OF SCIENCE & TECHNOLOGY (TW) 2008-04-29 US disclosed
US-20060241187-A1 Compound with antitumor activity and preparation method therefor NATIONAL TAIWAN UNIVERSITY OF SCIENCE AND TECHNOLOGY (TW) 2006-10-26 US disclosed
US-6562422-B1 Polymer for optical compensatory films for display panels INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2003-05-13 US disclosed
US-6562422-B1 Polymer for optical compensatory films for display panels INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2003-05-13 US disclosed
US-6054554-A HEAT RESISTANT; RADIATION TRANSPARENT KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2000-04-25 US disclosed
EP-0655434-B1 Aromatic diamine compounds useful for electroluminescence device NISSHIN SPINNING (JP) 1996-09-25 EP disclosed
JP-H07145116-A AROMATIC DIAMINE COMPOUND NISSHINBO IND INC 1995-06-06 JP disclosed
EP-0655434-A1 Aromatic diamine compounds useful for electroluminescence device NISSHINBO INDUSTRIES, INC. (JP) 1995-05-31 EP disclosed
US-5420351-A Charge transport compounds for electrography NISSHINBO INDUSTRIES, INC. (JP) 1995-05-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060241187-A1 Compound with antitumor activity and preparation method therefor WEE1, WEE2, CYP51A1 ALDH1A1 206/4885LMNA 2945/4885PGR 2516/4885
US-20230200218-A1 LIGHT-EMITTING DEVICE INCLUDING AMINE COMPOUND, ELECTRONIC APPARATUS INCLUDING THE LIGHT-EMITTING DEVICE, AND THE AMINE COMPOUND SLC18A1, CRY1, AADAT ALDH1A1 9/4885LMNA 2160/4885PGR 3047/4885
US-20230157157-A1 LIGHT-EMITTING DEVICE INCLUDING DIAMINE-BASED COMPOUND, ELECTRONIC APPARATUS INCLUDING THE LIGHT-EMITTING DEVICE, AND THE DIAMINE-BASED COMPOUND AOC1, DDT, DTD1 ALDH1A1 9/4885LMNA 4018/4885PGR 4394/4885
US-11785841-B2 Compound, display panel and display apparatus C1S, CDK20, CEP170 ALDH1A1 1239/4885LMNA 2044/4885PGR 1720/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.