Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OXTR | P30559 | 1/20 | 0.35 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.32 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.32 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.32 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.32 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.32 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | F10 | P00742 | 1/20 | 0.32 |
| ▸ | TIPARP | Q7Z3E1 | 2/20 | 0.32 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.31 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.31 |
| ▸ | RBP4 | P02753 | 2/20 | 0.31 |
| ▸ | SFRP1 | Q8N474 | 1/20 | 0.31 |
| ▸ | TTR | P02766 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27137184 | 0.89 | HSD11B1 (0.35) | MGLLHSD11B1PRSS1PRSS2PRSS3 | |
| SCHEMBL27137731 | 0.85 | RBP4 (0.38) | MGLLHSD11B1PRSS1PRSS2PRSS3 | |
| SCHEMBL30015004 | 0.85 | RBP4 (0.38) | MGLLHSD11B1PRSS1PRSS2PRSS3 | |
| SCHEMBL27147218 | 0.83 | DDB1 (0.35) | MGLLHSD11B1HRH3 | |
| SCHEMBL31024405 | 0.83 | GPR119 (0.40) | — | |
| SCHEMBL27123951 | 0.83 | GPR119 (0.40) | — | |
| SCHEMBL30014759 | 0.79 | MGLL (0.38) | MGLLHSD11B1HRH3SOS1 | |
| SCHEMBL27141895 | 0.79 | MGLL (0.38) | MGLLHSD11B1HRH3SOS1 | |
| SCHEMBL29201746 | 0.78 | MGLL (0.39) | MGLLHSD11B1 | |
| SCHEMBL29281606 | 0.78 | DDB1 (0.38) | MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4328219-A1 | SOS1 DEGRADING AGENT AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | Shanghai Leadingtac Pharmaceutical Co. Ltd. (CN) | 2024-02-28 | — | — | EP | disclosed |