Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | CA7 | P43166 | 1/20 | 0.54 |
| ▸ | CA9 | Q16790 | 1/20 | 0.54 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.51 |
| ▸ | ALPL | P05186 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.47 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5960683 | 0.84 | SMN1; SMN2 (0.67) | CA12CA1CA2CA7CA9 | |
| SCHEMBL25318370 | 0.83 | MAPT (0.43) | CA12CA1CA2CA7CA9 | |
| SCHEMBL2183386 | 0.82 | PKM (0.55) | CA12CA1CA2CA7CA9 | |
| SCHEMBL29551296 | 0.82 | PKM (0.55) | CA12CA1CA2CA7CA9 | |
| SCHEMBL669063 | 0.82 | GAA (0.54) | CA12CA1CA2CA7CA9 | |
| SCHEMBL13290777 | 0.82 | CA12 (0.52) | CA12CA1CA2CA7CA9 | |
| SCHEMBL17318079 | 0.82 | CA12 (0.52) | CA12CA1CA2CA7CA9 | |
| SCHEMBL29482639 | 0.82 | TRPV4 (0.68) | CA12CA1CA2CA7CA9 | |
| SCHEMBL74997 | 0.82 | TRPV4 (0.68) | CA12CA1CA2CA7CA9 | |
| SCHEMBL9705968 | 0.82 | GAA (0.54) | CA12CA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140038822-A1 | USE OF SUBSTITUTED SPIROCYCLIC SULFONAMIDOCARBOXYLIC ACIDS, CARBOXYLIC ESTERS THEREOF, CARBOXAMIDES THEREOF AND CARBONITRILES THEREOF OR SALTS THEREOF FOR ENHANCEMENT OF STRESS TOLERANCE IN PLANTS | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-02-06 | — | — | US | disclosed |
| EP-2186637-B1 | A lithographic printing plate | AGFA GRAPHICS NV (BE) | 2012-05-02 | — | — | EP | disclosed |
| US-20110315034-A1 | LITHOGRAPHIC PRINTING PLATE | AGFA GRAPHICS NV (BE) | 2011-12-29 | — | — | US | disclosed |
| US-20110315034-A1 | LITHOGRAPHIC PRINTING PLATE | AGFA GRAPHICS NV (BE) | 2011-12-29 | — | — | US | disclosed |
| US-8071795-B2 | Hypoxia inducible factor (Hif); for modulating mRNA translation within cells; prevents excessive vascularization | EMORY UNIVERSITY (US) | 2011-12-06 | — | — | US | disclosed |
| EP-2186637-A1 | A lithographic printing plate | Agfa Graphics N.V. (BE) | 2010-05-19 | — | — | EP | disclosed |
| US-20080226622-A1 | Hif Inhibitors | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2008-09-18 | — | — | US | disclosed |
| US-20080194629-A1 | 3-Mono-and 3,5-Disubstituted Piperidine Derivatives as Renin Inhibitors | BAESCHLIN DANIEL KASPAR | 2008-08-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080226622-A1 | Hif Inhibitors | HIF1AN, HIF1A, EGLN3 | CA12 589/4885CA1 477/4885CA2 161/4885 |
| US-20140038822-A1 | USE OF SUBSTITUTED SPIROCYCLIC SULFONAMIDOCARBOXYLIC ACIDS, CARBOXYLIC ESTERS THEREOF, CARBOXAMIDES THEREOF AND CARBONITRILES THEREOF OR SALTS THEREOF FOR ENHANCEMENT OF STRESS TOLERANCE IN PLANTS | STS, SCLY, TST | CA12 412/4885CA1 261/4885CA2 110/4885 |
| US-20080194629-A1 | 3-Mono-and 3,5-Disubstituted Piperidine Derivatives as Renin Inhibitors | REN, ACE, AGTR1 | CA12 4247/4885CA1 2717/4885CA2 724/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.