Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Salicylic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.41 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.41 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | CA6 | P23280 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Salicylic Acid SCHEMBL31344157 | 1.00 | ALDH1A1 (0.43) | ALDH1A1LMNAALOX12KDM4EBLM | |
| Benzoic Acid SCHEMBL27199877 | 0.86 | BLM (0.45) | ALDH1A1LMNAKDM4EBLMALOX15 | |
| Benzoic Acid SCHEMBL31344213 | 0.86 | BLM (0.45) | ALDH1A1LMNAKDM4EBLMALOX15 | |
| Acetic Acid SCHEMBL31344208 | 0.86 | KDM4E (0.48) | ALDH1A1LMNAKDM4EBLMALOX15 | |
| Acetic Acid SCHEMBL27199871 | 0.86 | KDM4E (0.48) | ALDH1A1LMNAKDM4EBLMALOX15 | |
| Salicylic Acid SCHEMBL27199836 | 0.86 | AADAT (0.42) | ALDH1A1KDM4EBLMALOX15CHRNB2 | |
| Salicylic Acid SCHEMBL31344154 | 0.86 | AADAT (0.42) | ALDH1A1KDM4EBLMALOX15CHRNB2 | |
| Salicylic Acid SCHEMBL27199872 | 0.84 | PARP1 (0.42) | ALDH1A1LMNAALOX12KDM4EBLM | |
| Salicylic Acid SCHEMBL31344145 | 0.84 | PARP1 (0.42) | ALDH1A1LMNAALOX12KDM4EBLM | |
| Salicylic Acid SCHEMBL31344212 | 0.83 | CHRNB2 (0.40) | ALDH1A1LMNAALOX12KDM4EBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4683527-A1 | VAPORIZABLE ALKALOID COMPOSITIONS AND METHODS OF USE THEREOF | Ready Mix Naturals, LLC (US) | 2026-01-28 | — | — | EP | disclosed |
| US-20250289796-A1 | COMPOSITIONS AND METHODS OF USE THEREOF | Ready Mix Naturals, LLC (US) | 2025-09-18 | — | — | US | disclosed |
| US-12358888-B2 | Vaporizable alkaloid compositions and methods of use thereof | Ready Mix Naturals, LLC (US) | 2025-07-15 | — | — | US | disclosed |
| US-12358889-B2 | Vaporizable alkaloid compositions and methods of use thereof | Ready Mix Naturals, LLC (US) | 2025-07-15 | — | — | US | disclosed |
| WO-2024155297-A1 | VAPORIZABLE ALKALOID COMPOSITIONS AND METHODS OF USE THEREOF | Ready Mix Naturals, LLC (US) | 2024-07-25 | — | — | WO | disclosed |
| US-20240246930-A1 | VAPORIZABLE ALKALOID COMPOSITIONS AND METHODS OF USE THEREOF | Ready Mix Naturals, LLC (US) | 2024-07-25 | — | — | US | disclosed |
| US-11964958-B1 | Vaporizable alkaloid compositions and methods of use thereof | Ready Mix Naturals, LLC (US) | 2024-04-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240246930-A1 | VAPORIZABLE ALKALOID COMPOSITIONS AND METHODS OF USE THEREOF | SRM, SCLY, SMOX | ALDH1A1 842/4885LMNA 4520/4885ALOX12 4422/4885 |
| US-11964958-B1 | Vaporizable alkaloid compositions and methods of use thereof | SRM, SCLY, SMOX | ALDH1A1 842/4885LMNA 4520/4885ALOX12 4422/4885 |
| US-20250289796-A1 | COMPOSITIONS AND METHODS OF USE THEREOF | OR10J3, TRPA1, TAS2R3 | ALDH1A1 912/4885LMNA 3704/4885ALOX12 847/4885 |
| US-12358888-B2 | Vaporizable alkaloid compositions and methods of use thereof | SRM, SCLY, SMOX | ALDH1A1 842/4885LMNA 4520/4885ALOX12 4422/4885 |
| US-12358889-B2 | Vaporizable alkaloid compositions and methods of use thereof | SRM, SCLY, SMOX | ALDH1A1 842/4885LMNA 4520/4885ALOX12 4422/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.