Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 2/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | CES2 | O00748 | 2/20 | 0.33 |
| ▸ | CES1 | P23141 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24749862 | 0.83 | TDP1 (0.44) | ALDH1A1LMNASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL24748979 | 0.75 | KDM4E (0.39) | ALDH1A1LMNASMN1; SMN2KMT2AHPGD | |
| SCHEMBL24748942 | 0.75 | CA1 (0.43) | ALDH1A1LMNASMN1; SMN2KMT2AHPGD | |
| SCHEMBL24748614 | 0.75 | CYP1A2 (0.43) | ALDH1A1LMNASMN1; SMN2KMT2AHPGD | |
| SCHEMBL24748595 | 0.72 | KDM4E (0.38) | ALDH1A1SMN1; SMN2KMT2AMEN1TDP1 | |
| SCHEMBL9856924 | 0.68 | ALDH1A1 (0.65) | SRD5A2AKR1C3ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL11016599 | 0.66 | SRD5A2 (0.50) | SRD5A2AKR1C3ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL24749034 | 0.65 | GLA (0.42) | ALDH1A1LMNASMN1; SMN2KMT2AHPGD | |
| SCHEMBL10988695 | 0.65 | SRD5A2 (0.63) | SRD5A2ALDH1A1LMNASMN1; SMN2KMT2A | |
| SCHEMBL3288949 | 0.64 | LMNA (0.59) | SRD5A2AKR1C3ALDH1A1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11974991-B1 | Adenosine receptor activity of methyl/ethyl 3-(substituted benzoyl)-6,8-dimethylindolizine-2-substituted-1-carboxylates | King Faisal University (SA) | 2024-05-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11974991-B1 | Adenosine receptor activity of methyl/ethyl 3-(substituted benzoyl)-6,8-dimethylindolizine-2-substituted-1-carboxylates | ADORA2A, ADORA1, ADORA3 | SRD5A2 2524/4885AKR1C3 1015/4885ALDH1A1 943/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.