SCHEMBL27247338

SCHEMBL27247338

CN(Cc1ccccc1)c1ccc2cc(CNC(=O)C3(C)CC3)[nH]c2c1

nearest known ligand 0.43

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ METTL3 Q86U44 15/20 0.43
▸ METTL14 Q9HCE5 15/20 0.43
▸ SLC16A3 O15427 1/20 0.41
▸ SLC16A1 P53985 1/20 0.41
▸ RXRA P19793 1/20 0.39
▸ RXRB P28702 1/20 0.39
▸ RXRG P48443 1/20 0.39
▸ IDO1 P14902 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27247155 0.81 RET (0.42) METTL3METTL14IDO1
SCHEMBL27247424 0.80 MAOB (0.49) —
SCHEMBL27383634 0.79 DAO (0.46) METTL3METTL14
SCHEMBL27247738 0.79 METTL3 (0.38) METTL3METTL14
SCHEMBL27247390 0.78 METTL3 (0.39) METTL3METTL14
SCHEMBL30920223 0.77 HRH4 (0.40) METTL3METTL14
SCHEMBL27246874 0.77 HRH4 (0.40) METTL3METTL14IDO1
SCHEMBL30920783 0.76 MASP2 (0.39) METTL3METTL14
SCHEMBL27246904 0.76 MASP2 (0.39) METTL3METTL14
SCHEMBL30920709 0.75 MTNR1A (0.57) —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4601635-A2 INHIBITORS OF SOLUTE CARRIER FAMILY 6A MEMBER 19 (SLC6A19) AND METHODS OF USE THEREOF Maze Therapeutics, Inc. (US) 2025-08-20 — — EP disclosed
US-20240199546-A1 INHIBITORS OF SOLUTE CARRIER FAMILY 6A MEMBER 19 (SLC6A19) AND METHODS OF USE THEREOF HERCULES CAPITAL, INC., AS AGENT 2024-06-20 — — US disclosed
WO-2024081748-A2 INHIBITORS OF SOLUTE CARRIER FAMILY 6A MEMBER 19 (SLC6A19) AND METHODS OF USE THEREOF MAZE THERAPEUTICS, INC. (US) 2024-04-18 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240199546-A1 INHIBITORS OF SOLUTE CARRIER FAMILY 6A MEMBER 19 (SLC6A19) AND METHODS OF USE THEREOF SLC6A19, SLC2A9, SLC6A3 METTL3 2034/4885METTL14 2352/4885SLC16A3 76/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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