SCHEMBL2727249

SCHEMBL2727249

NC(=O)C(C(=O)O)C(=O)O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.43
LDHA P00338 1/20 0.38
LDHB P07195 1/20 0.38
ALDH1A1 P00352 4/20 0.36
LMNA P02545 3/20 0.36
TDP1 Q9NUW8 3/20 0.36
OR51E2 Q9H255 1/20 0.36
TSHR P16473 1/20 0.35
THRB P10828 1/20 0.35
RECQL P46063 1/20 0.35
HPGD P15428 2/20 0.33
ALOX15 P16050 2/20 0.33
KMT2A Q03164 2/20 0.33
HSD17B10 Q99714 2/20 0.33
ABCB11 O95342 1/20 0.33
F2 P00734 1/20 0.33
TP53 P04637 1/20 0.33
KDM4E B2RXH2 1/20 0.33
MEN1 O00255 1/20 0.33
MAPT P10636 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8828681 0.92 ACHE (0.43) ACHELDHALDHBALDH1A1LMNA
SCHEMBL1588902 0.79 LMNA (0.46) ACHELDHALDHBALDH1A1LMNA
SCHEMBL445370 0.74 ALDH1A1 (0.46) ALDH1A1LMNATDP1OR51E2TSHR
SCHEMBL17818666 0.70 ALDH1A1 (0.43) ALDH1A1LMNATDP1OR51E2TSHR
SCHEMBL27535153 0.70 ALDH1A1 (0.43) ALDH1A1LMNATDP1OR51E2TSHR
SCHEMBL30775137 0.69 ACHE (0.43) ACHELDHALDHBALDH1A1LMNA
SCHEMBL1010979 0.67
SCHEMBL9542105 0.67 LMNA (0.47) ACHEALDH1A1LMNATDP1OR51E2
SCHEMBL2735769 0.67
SCHEMBL27471960 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0310971-B1 CATHODICALLY DEPOSITABLE AQUEOUS ELECTRODEPOSITION COMPOSITION AND ITS USE Herberts Gesellschaft mit beschränkter Haftung (DE) 1992-07-08 EP claimed
US-5039720-A Aqueous electrophoretic enamel coating materials, which can be deposited at the cathode crosslinked with methane tricarboxylic acid amides of malonic acid derivatives HOECHST AKTIENGESELLSCHAFT (DE) 1991-08-13 US claimed
CN-1013117-B PROCESS FOR PREPARATING HARDENING PRODUCTS BASED ON OLEFINIC UNSATURATED COMPOUNDS AND COMPOUNDS CONTAINING ACTIVE HYDROGEN AND THE USE THEREOF THE SYSTEM IN DOUBLE COMPOSITIONS PAINT HOECHST AG (DE) 1991-07-10 CN claimed
CN-86107731-A Is the method and the application of this system in double compositions paint of feedstock production cured product with alefinically unsaturated compounds with the compound that contains reactive hydrogen 1987-06-17 CN claimed
JP-1121376-A None JP disclosed
JP-10251372-A None JP disclosed
US-10611861-B2 Multifunctional monomers, methods for making multifunctional monomers, polymerizable compositions and products formed thereform NIPPON SHOKUBAI CO., LTD. (JP) 2020-04-07 US disclosed
US-10604601-B2 Multifunctional monomers, methods for making multifunctional monomers, polymerizable compositions and products formed therefrom SIRRUS, INC. (US) 2020-03-31 US disclosed
EP-3517523-A1 MULTIFUNCTIONAL MONOMERS AND METHODS FOR MAKING THEM Sirrus, Inc. (US) 2019-07-31 EP disclosed
US-20180346615-A1 MULTIFUNCTIONAL MONOMERS, METHODS FOR MAKING MULTIFUNCTIONAL MONOMERS, POLYMERIZABLE COMPOSITIONS AND PRODUCTS FORMED THEREFORM NIPPON SHOKUBAI CO., LTD. (JP) 2018-12-06 US disclosed
EP-2768917-B1 MULTIFUNCTIONAL MONOMERS AND METHODS FOR MAKING THEM SIRRUS INC (US) 2018-12-05 EP disclosed
US-20180327525-A1 MULTIFUNCTIONAL MONOMERS, METHODS FOR MAKING MULTIFUNCTIONAL MONOMERS, POLYMERIZABLE COMPOSITIONS AND PRODUCTS FORMED THEREFORM NIPPON SHOKUBAI CO., LTD. (JP) 2018-11-15 US disclosed
US-5426156-A Two-component coatings with enamine groups cured rapidly; from transesterification, amination in presence of Lewis or Bronsted base; hydroxy unsaturated ester or amide polymers; blends; automobile paints HERBERTS GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1995-06-20 US disclosed
US-5039720-A Aqueous electrophoretic enamel coating materials, which can be deposited at the cathode crosslinked with methane tricarboxylic acid amides of malonic acid derivatives HOECHST AKTIENGESELLSCHAFT (DE) 1991-08-13 US disclosed
US-5039720-A Aqueous electrophoretic enamel coating materials, which can be deposited at the cathode crosslinked with methane tricarboxylic acid amides of malonic acid derivatives HOECHST AKTIENGESELLSCHAFT (DE) 1991-08-13 US disclosed
US-5039720-A Aqueous electrophoretic enamel coating materials, which can be deposited at the cathode crosslinked with methane tricarboxylic acid amides of malonic acid derivatives HOECHST AKTIENGESELLSCHAFT (DE) 1991-08-13 US disclosed
CN-1013117-B PROCESS FOR PREPARATING HARDENING PRODUCTS BASED ON OLEFINIC UNSATURATED COMPOUNDS AND COMPOUNDS CONTAINING ACTIVE HYDROGEN AND THE USE THEREOF THE SYSTEM IN DOUBLE COMPOSITIONS PAINT HOECHST AG (DE) 1991-07-10 CN disclosed
JP-H01121376-A AQUEOUS ELECTROPHORETIC ENAMEL COATING MATERIAL WHICH CAN BE DEPOSITED AT CATHODE HERBERTS GMBH 1989-05-15 JP disclosed
CN-86107731-A Is the method and the application of this system in double compositions paint of feedstock production cured product with alefinically unsaturated compounds with the compound that contains reactive hydrogen 1987-06-17 CN disclosed
CN-86107731-A Is the method and the application of this system in double compositions paint of feedstock production cured product with alefinically unsaturated compounds with the compound that contains reactive hydrogen 1987-06-17 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10604601-B2 Multifunctional monomers, methods for making multifunctional monomers, polymerizable compositions and products formed therefrom BHMT2, MACF1, BHMT ACHE 2135/4885LDHA 1678/4885LDHB 2012/4885
US-20180327525-A1 MULTIFUNCTIONAL MONOMERS, METHODS FOR MAKING MULTIFUNCTIONAL MONOMERS, POLYMERIZABLE COMPOSITIONS AND PRODUCTS FORMED THEREFORM MACF1, BHMT2, MTHFD2 ACHE 2350/4885LDHA 1638/4885LDHB 1856/4885
US-10611861-B2 Multifunctional monomers, methods for making multifunctional monomers, polymerizable compositions and products formed thereform MACF1, BHMT2, MTHFD2 ACHE 2350/4885LDHA 1638/4885LDHB 1856/4885
US-20180346615-A1 MULTIFUNCTIONAL MONOMERS, METHODS FOR MAKING MULTIFUNCTIONAL MONOMERS, POLYMERIZABLE COMPOSITIONS AND PRODUCTS FORMED THEREFORM MACF1, BHMT2, MTHFD2 ACHE 2350/4885LDHA 1638/4885LDHB 1856/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.