Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC5A2 | P31639 | 1/20 | 0.49 |
| ▸ | IDH1 | O75874 | 1/20 | 0.42 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.42 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.42 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.41 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.40 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | DAO | P14920 | 1/20 | 0.39 |
| ▸ | PRKCI | P41743 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11576495 | 0.87 | TSHR (0.52) | IDH1ENPP2ESR1ESR2PRSS1 | |
| SCHEMBL15694827 | 0.85 | CALM1 (0.55) | SLC5A2IDH1SRD5A2PRSS1PRSS2 | |
| SCHEMBL9999688 | 0.85 | ENPP2 (0.54) | IDH1ENPP2S1PR1PRSS1PRSS2 | |
| SCHEMBL8992941 | 0.84 | LTA4H (0.49) | SLC5A2IDH1ESR1ESR2SAE1 | |
| SCHEMBL4430768 | 0.83 | TSHR (0.59) | SLC5A2IDH1ENPP2PRSS1PRSS2 | |
| SCHEMBL8992802 | 0.83 | SRD5A2 (0.50) | MAP2K4SRD5A2ESR1ESR2PRSS1 | |
| SCHEMBL11087087 | 0.81 | LTA4H (0.53) | SLC5A2IDH1SAE1UBA2TSHR | |
| SCHEMBL19440607 | 0.81 | MTNR1A (0.43) | SLC5A2IDH1ENPP2S1PR1PRSS1 | |
| SCHEMBL12782166 | 0.80 | IDH1 (0.42) | IDH1ENPP2PRSS1PRSS2PRSS3 | |
| SCHEMBL12002732 | 0.80 | IDH1 (0.42) | IDH1ENPP2PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4393937-A1 | STEROID COMPOUND AND CONJUGATE THEREOF | Duality Biologics (Suzhou) Co., Ltd. (CN) | 2024-07-03 | — | — | EP | disclosed |