Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 2/20 | 0.58 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.58 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.46 |
| ▸ | SIRT6 | Q8N6T7 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27318291 | 0.90 | PKM (0.52) | AKR1C3AKR1C2AKR1C1MAPTHSD17B10 | |
| SCHEMBL27344721 | 0.84 | SMN1; SMN2 (0.47) | MAPTTSHRTDP1LMNARECQL | |
| SCHEMBL27319189 | 0.83 | GFER (0.49) | LMNARECQLKMT2A | |
| SCHEMBL8809866 | 0.77 | RAB9A (0.64) | AKR1C3AKR1C2AKR1C1MAPTHSD17B10 | |
| SCHEMBL27322188 | 0.77 | PTGS2 (0.59) | HSD17B10LMNARECQLKMT2AALDH1A1 | |
| SCHEMBL27325273 | 0.76 | KMT2A (0.54) | MAPTLMNAKMT2AMEN1ALDH1A1 | |
| SCHEMBL28148161 | 0.76 | NPC1 (0.56) | MAPTLMNAHTT | |
| SCHEMBL27315064 | 0.76 | ALDH1A1 (0.50) | MAPTHSD17B10POLBPKMTDP1 | |
| SCHEMBL27311725 | 0.76 | ALDH1A1 (0.48) | MAPTTSHRLMNAKMT2AALDH1A1 | |
| SCHEMBL27408901 | 0.76 | KMT2A (0.49) | MAPTHSD17B10POLBTDP1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1051074-C | Isoxazole-4-carboxamides and hydroxyalkylidenecyanoacetamides pharmaceuticals containing these compounds and their use | HOECHST AG (DE) | 2000-04-05 | — | — | CN | disclosed |
| CN-1056684-A | Different azoles-4-carboxylic acid amides and hydroxy alkylidene Malonamide nitrile contains the medicine of these compounds and their application | HOECHST AG (DE) | 1991-12-04 | — | — | CN | disclosed |