SCHEMBL27363219

SCHEMBL27363219

CCCCCCCCc1ccc2nn(-c3ccccc3)nc2c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.49
MAPT P10636 3/20 0.49
NPC1 O15118 3/20 0.49
ALDH1A1 P00352 3/20 0.49
RAB9A P51151 3/20 0.49
MEN1 O00255 2/20 0.49
KMT2A Q03164 2/20 0.49
STAT1 P42224 1/20 0.49
TDP1 Q9NUW8 1/20 0.47
HPGD P15428 3/20 0.47
CNR1 P21554 1/20 0.44
CNR2 P34972 1/20 0.44
HSD11B1 P28845 1/20 0.43
SMN1; SMN2 Q16637 3/20 0.43
TP53 P04637 2/20 0.43
NFKB1 P19838 2/20 0.43
NFKB2 Q00653 2/20 0.43
RELA Q04206 2/20 0.43
CYP1A2 P05177 1/20 0.43
GAA P10253 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29061455 0.85 FAAH (0.50) KDM4EMAPTALDH1A1RAB9AMEN1
SCHEMBL27550693 0.84 DHFR (0.52) KDM4EMAPTTDP1HPGDCNR1
SCHEMBL27749246 0.84 GPR3 (0.46) KDM4EALDH1A1HSD11B1TP53HSD17B10
SCHEMBL5666375 0.80 NPC1 (0.43) NPC1ALDH1A1RAB9A
SCHEMBL28560255 0.79 ALDH1A1 (0.54) KDM4EMAPTNPC1ALDH1A1RAB9A
SCHEMBL29216527 0.79 MAPT (0.53) KDM4EMAPTNPC1RAB9AMEN1
SCHEMBL29250231 0.76 HSD11B1 (0.40) KDM4EMAPTNPC1RAB9ATDP1
SCHEMBL27478937 0.75 PTGS2 (0.55) KDM4EALDH1A1CNR1CNR2TP53
SCHEMBL4468022 0.75 PTGS2 (0.55) KDM4EALDH1A1CNR1CNR2TP53
SCHEMBL12755311 0.75 LMNA (0.55) KDM4ENPC1ALDH1A1RAB9ATP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1320049-C Synergistic UV absorber combination CIBA SC HOLDING AG (CH) 2007-06-06 CN claimed
CN-1685008-A Synergistic UV absorber combination CIBA SC HOLDING AG (CH) 2005-10-19 CN claimed
CN-101679764-A Low-dust additive and pigment blends with improved color CIBA HOLDING INC 2010-03-24 CN disclosed
CN-1320049-C Synergistic UV absorber combination CIBA SC HOLDING AG (CH) 2007-06-06 CN disclosed
CN-1250626-C Candle wax stabilized by combination of UV absorber plus selected hindered amine CIBA SC HOLDING AG (CH) 2006-04-12 CN disclosed
CN-1685008-A Synergistic UV absorber combination CIBA SC HOLDING AG (CH) 2005-10-19 CN disclosed
CN-1180008-C Method for content protection using durable UV absorbers �������⻯ѧƷ�ع����޹�˾ 2004-12-15 CN disclosed
CN-1427866-A Method of content protection with durable UV absorbers CIBA SC HOLDING AG (CH) 2003-07-02 CN disclosed
CN-1420907-A Candle wax stabilized by combination of UV absorber plus selected hindered amine CIBA SC HOLDING AG (CH) 2003-05-28 CN disclosed
CN-1059899-C Novel 2-(2-hydroxy-3-alpha-cumyl-5-alkylphenyl)-2H-benzotriazoles CIBA GEIGY AG (CH) 2000-12-27 CN disclosed