Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 7/20 | 0.41 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25383292 | 0.87 | L3MBTL1 (0.50) | KLKB1ACHEMAPTALDH1A1L3MBTL1 | |
| SCHEMBL25381150 | 0.85 | L3MBTL1 (0.42) | KLKB1ACHEMAPTALDH1A1L3MBTL1 | |
| SCHEMBL27364247 | 0.82 | MAPT (0.53) | KLKB1MAPTALDH1A1LMNAMAPK1 | |
| SCHEMBL25381515 | 0.82 | GRM2 (0.47) | KLKB1ACHELMNAL3MBTL1NPSR1 | |
| SCHEMBL27286140 | 0.81 | ALDH1A1 (0.62) | KLKB1MAPTALDH1A1LMNAMAPK1 | |
| SCHEMBL27364070 | 0.80 | KLKB1 (0.55) | KLKB1MAPTALDH1A1LMNAMAPK1 | |
| SCHEMBL27286135 | 0.79 | MAPT (0.43) | KLKB1ACHEMAPTALDH1A1LMNA | |
| SCHEMBL27364059 | 0.78 | LMNA (0.49) | KLKB1ACHEMAPTALDH1A1LMNA | |
| SCHEMBL28008334 | 0.76 | KLKB1 (0.44) | KLKB1ACHEMAPTALDH1A1L3MBTL1 | |
| SCHEMBL27364069 | 0.75 | KLKB1 (0.44) | KLKB1MAPTALDH1A1LMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024026483-A2 | CDK2 INHIBITORS AND METHODS OF USING THE SAME | CEDILLA THERAPEUTICS, INC. (US) | 2024-02-01 | — | — | WO | disclosed |