Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7849227 | 0.72 | TRPA1 (0.33) | TRPA1 | |
| SCHEMBL27528699 | 0.72 | TRPA1 (0.33) | TRPA1 | |
| SCHEMBL7845259 | 0.72 | TRPA1 (0.33) | TRPA1 | |
| SCHEMBL27499136 | 0.69 | TSHR (0.31) | — | |
| SCHEMBL7847311 | 0.68 | GPR84 (0.41) | TRPA1 | |
| SCHEMBL8555 | 0.67 | TRPA1 (0.35) | TRPA1 | |
| SCHEMBL7852096 | 0.66 | ALDH1A1 (0.39) | — | |
| SCHEMBL7851348 | 0.65 | L3MBTL1 (0.35) | — | |
| SCHEMBL27529392 | 0.64 | MEN1 (0.33) | TRPA1 | |
| SCHEMBL20145049 | 0.63 | TRPA1 (0.39) | TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116964048-A | Bicyclic tetrahydroazepine derivatives for the treatment of cancer | 豪夫迈·罗氏有限公司 | 2023-10-27 | — | — | CN | disclosed |
| CN-107889487-A | Bicyclic tetrahydrothiazaaza derivatives for the treatment of tumors and/or infectious diseases | 阿派隆生物制剂股份公司 | 2018-04-06 | — | — | CN | disclosed |
| CN-1195748-C | 1,2-benzothiazepines for the treatment of hyperlipidemic diseases | SEARLE & CO (US) | 2005-04-06 | — | — | CN | disclosed |
| CN-1414958-A | Nonpeptide substituted benzothiazepines as vasopressin antagonists | ORTHO MCNEIL PHARM INC (US) | 2003-04-30 | — | — | CN | disclosed |
| CN-1346351-A | 1,2-benzothiazepines for the treatment of hyperlipidemic diseases | SEARLE & CO (US) | 2002-04-24 | — | — | CN | disclosed |
| CN-1059674-C | Reduced blood lipid benzothiazepine * | WELLCOME FOUND (GB) | 2000-12-20 | — | — | CN | disclosed |