Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.48 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | CES2 | O00748 | 1/20 | 0.45 |
| ▸ | CES1 | P23141 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 6/20 | 0.42 |
| ▸ | RAB9A | P51151 | 6/20 | 0.42 |
| ▸ | PKM | P14618 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | PTPRA | P18433 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL28880764 | 0.91 | LMNA (0.52) | ALDH1A1LMNANAPRTP4HTML3MBTL1 | |
| SCHEMBL363240 | 0.83 | — | — | |
| Formic Acid SCHEMBL27440282 | 0.80 | CES2 (0.41) | ALDH1A1LMNANAPRTP4HTML3MBTL1 | |
| Phosphoric Acid SCHEMBL28997991 | 0.80 | FDPS (0.44) | ALDH1A1LMNANAPRTP4HTML3MBTL1 | |
| Boric Acid SCHEMBL27872370 | 0.79 | KDM4E (0.42) | ALDH1A1LMNANAPRTP4HTML3MBTL1 | |
| Dipyridyl SCHEMBL11231947 | 0.77 | KDM4E (0.67) | ALDH1A1LMNANAPRTP4HTML3MBTL1 | |
| Dipyridyl SCHEMBL4881410 | 0.77 | KDM4E (0.67) | ALDH1A1LMNANAPRTP4HTML3MBTL1 | |
| Dipyridyl SCHEMBL9641711 | 0.77 | KDM4E (0.67) | ALDH1A1LMNANAPRTP4HTML3MBTL1 | |
| Dipyridyl SCHEMBL8773554 | 0.76 | KDM4E (0.64) | ALDH1A1LMNANAPRTP4HTML3MBTL1 | |
| Acetic Acid SCHEMBL7464988 | 0.76 | ALDH1A1 (0.54) | ALDH1A1LMNANAPRTP4HTML3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1117628-C | Bimetallic catalyst for homogeneous methanol carbonylation and its prepn | CHINESE ACAD INST CHEMISTRY (CN) | 2003-08-13 | — | — | CN | claimed |
| CN-1349855-A | Bimetallic catalyst for homogeneous methanol carbonylation and its prepn | CHINESE ACAD INST CHEMISTRY (CN) | 2002-05-22 | — | — | CN | claimed |
| CN-103038206-B | Carbonylation method | 塞拉尼斯国际公司 | 2016-10-05 | — | — | CN | disclosed |
| CN-102471209-B | Acetic acid production by way of carbonylation with enhanced reaction and flashing | CELANESE INT CORP (US) | 2014-05-28 | — | — | CN | disclosed |
| CN-103038206-A | Carbonylation process | CELANESE INTERNALTIONAL CORP | 2013-04-10 | — | — | CN | disclosed |
| CN-102471209-A | Acetic acid production by carbonylation with enhanced reaction and flash | CELANESE INT CORP (US) | 2012-05-23 | — | — | CN | disclosed |
| CN-1117628-C | Bimetallic catalyst for homogeneous methanol carbonylation and its prepn | CHINESE ACAD INST CHEMISTRY (CN) | 2003-08-13 | — | — | CN | disclosed |
| CN-1349855-A | Bimetallic catalyst for homogeneous methanol carbonylation and its prepn | CHINESE ACAD INST CHEMISTRY (CN) | 2002-05-22 | — | — | CN | disclosed |