Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 5/20 | 0.47 |
| ▸ | LPAR5 | Q9H1C0 | 5/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA4 | P22748 | 1/20 | 0.45 |
| ▸ | CA5A | P35218 | 1/20 | 0.45 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11662190 | 0.90 | LMNA (0.47) | LPAR1LPAR5MAPK14ALDH1A1SMN1; SMN2 | |
| SCHEMBL27418971 | 0.82 | GCK (0.45) | LPAR1LPAR5ALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL7690257 | 0.81 | ALDH1A1 (0.59) | LPAR1LPAR5MAPK14ALDH1A1SMN1; SMN2 | |
| SCHEMBL2173776 | 0.77 | CA2 (0.62) | CYP2C9CYP2C19CA2CA4CA5A | |
| SCHEMBL27395622 | 0.76 | TSHR (0.56) | MAPK14ALDH1A1SMN1; SMN2HPGDCA2 | |
| SCHEMBL8282837 | 0.76 | LTA4H (0.56) | LPAR1LPAR5MAPK14ALDH1A1SMN1; SMN2 | |
| SCHEMBL172615 | 0.75 | HTR2A (0.55) | LPAR1LPAR5MAPK14ALDH1A1SMN1; SMN2 | |
| SCHEMBL28816731 | 0.75 | LTA4H (0.55) | LPAR1LPAR5ALDH1A1SMN1; SMN2CYP1A2 | |
| SCHEMBL232763 | 0.75 | SMN1; SMN2 (0.56) | LPAR1LPAR5ALDH1A1SMN1; SMN2CYP1A2 | |
| SCHEMBL5608673 | 0.74 | HPGD (0.62) | LPAR1LPAR5MAPK14ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1089614-A | Alpha-phosphonosulfonate squalene synthetase inhibitors and method | SQUIBB & SONS INC (US) | 1994-07-20 | — | — | CN | disclosed |