Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMEL1 | Q495T6 | 1/20 | 0.47 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.44 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20966406 | 0.84 | MMEL1 (0.53) | MMEL1CTRB1SPHK1NPSR1SMN1; SMN2 | |
| SCHEMBL20966402 | 0.84 | SPHK1 (0.58) | MMEL1CTRB1SPHK1SMN1; SMN2CYP2C19 | |
| SCHEMBL29208506 | 0.83 | CTRB1 (0.60) | CTRB1NPSR1KDM1ARCOR1ALDH1A1 | |
| SCHEMBL8549131 | 0.82 | FKBP1A (0.55) | MMEL1SMN1; SMN2CYP2C19FKBP1AALDH1A1 | |
| SCHEMBL14836855 | 0.81 | MMEL1 (0.52) | MMEL1CTRB1SPHK1SMN1; SMN2CYP2C19 | |
| SCHEMBL8549128 | 0.81 | NPSR1 (0.48) | MMEL1CTRB1NPSR1SMN1; SMN2FKBP1A | |
| SCHEMBL8549125 | 0.81 | NPSR1 (0.48) | MMEL1CTRB1NPSR1SMN1; SMN2FKBP1A | |
| SCHEMBL934366 | 0.80 | MMEL1 (0.58) | MMEL1CTRB1NPSR1FKBP1AALDH1A1 | |
| SCHEMBL2707345 | 0.80 | MMEL1 (0.58) | MMEL1CTRB1NPSR1FKBP1AALDH1A1 | |
| SCHEMBL21264915 | 0.80 | MMEL1 (0.49) | MMEL1CTRB1NPSR1SMN1; SMN2KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240217928-A1 | HALOACETHYDRAZIDES USEFUL AS AEP INHIBITORS | HOFFMANN-LA ROCHE INC. (US) | 2024-07-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240217928-A1 | HALOACETHYDRAZIDES USEFUL AS AEP INHIBITORS | NHERF1, ENPP1, ATP6AP1 | MMEL1 273/4885CTRB1 266/4885SPHK1 3390/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.