Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27453018 | 0.87 | PAX8 (0.53) | HPGDGAAALDH1A1POLBKDM4E | |
| SCHEMBL27453115 | 0.81 | LMNA (0.56) | ALDH1A1POLBKDM4ELMNAMEN1 | |
| SCHEMBL27451960 | 0.81 | PAX8 (0.54) | HPGDGAAALDH1A1KDM4ELMNA | |
| SCHEMBL27453119 | 0.77 | KMT2A (0.45) | HPGDGAAALDH1A1POLBKDM4E | |
| SCHEMBL27453023 | 0.74 | APP (0.43) | ALDH1A1POLBKDM4ELMNAKMT2A | |
| SCHEMBL27452583 | 0.73 | HPGD (0.57) | HPGDALDH1A1POLBKDM4ELMNA | |
| SCHEMBL5308738 | 0.71 | HPGD (1.00) | HPGDGAAALDH1A1POLBLMNA | |
| SCHEMBL27453112 | 0.71 | ALDH1A1 (0.42) | GAAALDH1A1POLBLMNAMEN1 | |
| SCHEMBL27452585 | 0.70 | RAB9A (0.58) | HPGDGAAALDH1A1POLBKDM4E | |
| SCHEMBL27452496 | 0.69 | ADORA2A (0.65) | HPGDALDH1A1POLBKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024145662-A1 | 2-SUBSTITUTED THIAZOLE AND BENZOTHIAZOLE COMPOSITIONS AND METHODS AS DUX4 INHIBITORS | ALTAY THERAPEUTICS, INC. (US) | 2024-07-04 | — | — | WO | disclosed |