Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 4/20 | 0.33 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.33 |
| ▸ | CCR3 | P51677 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.31 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8544796 | 0.85 | ALDH1A2 (0.35) | ATMCACNA1GCCR3GRIN2B | |
| SCHEMBL27486618 | 0.83 | ALDH1A1 (0.36) | CACNA1GCCR3 | |
| SCHEMBL27437868 | 0.71 | GRIN2B (0.50) | CCR3GRIN2BADRA1DADRA1AADRA1B | |
| SCHEMBL8544706 | 0.68 | GRIN2B (0.40) | GRIN2B | |
| SCHEMBL8543058 | 0.68 | CACNA1G (0.37) | ATMCACNA1GCCR3GRIN2B | |
| SCHEMBL11374861 | 0.64 | GMNN (0.57) | GRIN2BADRA1DADRA1AADRA1B | |
| SCHEMBL10462905 | 0.64 | SPHK2 (0.50) | — | |
| SCHEMBL7251269 | 0.64 | TRPV6 (0.49) | GRIN2BADRA1DADRA1AADRA1B | |
| SCHEMBL5411160 | 0.63 | ADRA1D (0.44) | ATMCCR3ADRA1DADRA1AADRA1B | |
| SCHEMBL6192571 | 0.62 | CCR3 (0.36) | ATMCCR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1128762-A | Benzyl piperidine derivatives | MERCK PATENT GMBH (DE) | 1996-08-14 | — | — | CN | disclosed |