⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27460680 | 0.81 | L3MBTL1 (0.43) | — | |
| SCHEMBL14336874 | 0.65 | LMNA (0.52) | — | |
| SCHEMBL25181538 | 0.61 | CHRNB2 (0.38) | — | |
| SCHEMBL30416628 | 0.61 | CHRNB2 (0.38) | — | |
| SCHEMBL5544837 | 0.60 | ME3 (0.46) | — | |
| SCHEMBL25428228 | 0.60 | AKR1C3 (0.44) | — | |
| SCHEMBL25174002 | 0.60 | MAPT (0.47) | — | |
| SCHEMBL759554 | 0.60 | GPR119 (0.47) | — | |
| SCHEMBL30392315 | 0.60 | ADRA2C (0.50) | — | |
| SCHEMBL27460728 | 0.60 | CHRNB2 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023244764-A1 | COMPOUNDS FOR THE TARGETED DEGRADATION OF SMARCA2 | C4 THERAPEUTICS, INC. (US) | 2023-12-21 | — | — | WO | disclosed |